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Investigation of Th17 cell differentiation in immunodeficiencies associated with high IgE levels and/or autoimmunity

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Objective: Hyper IgE Syndrome (HIES) and Common Variably Immunodeficiency (CVID) are immuno-deficiency diseases. HIES is characterized by recurrent skin abscesses, pneumonia, mucocutaneous fungal infections, eczama, eosinophilia and high serum IgE levels. CVID is characterized by recurrent bacterial infections in airways and gastrointestinal tract. In this study, differentiation of Th17 cells were aimed to be investigated in CVID and HIES patients.

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AKKOÇ T., Tevetoglu A., Ogulur I., Izgi A., AYDINER E., BARIŞ S., Bahceciler N., Barlan I., "Investigation of Th17 cell differentiation in immunodeficiencies associated with high IgE levels and/or autoimmunity", CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, cilt.1, sa.2, ss.96-102, 2011

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