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Microbial transformation of Astragalus sapogenins using Cunninghamella blakesleeana NRRL 1369 and Glomerella fusarioides ATCC 9552

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dc.contributor.authorKULA, CEYDA
dc.contributor.authorsBedir, Erdal; Kula, Ceyda; Oner, Ozlem; Altas, Melis; Tag, Ozgur; Ongen, Gaye
dc.date.accessioned2022-03-13T12:49:42Z
dc.date.accessioned2026-01-11T17:13:09Z
dc.date.available2022-03-13T12:49:42Z
dc.date.issued2015
dc.description.abstractThe microbial transformation of Astragalus sp. derived sapogenins, namely cycloastragenol, astragenol and cyclocanthogenol, by Cunninghamella blakesleeana NRRL 1369 and Glomerella fusarioides ATCC 9552 were investigated. The unique enzyme system of both fungi resulted hydroxylation, cyclization, dehydrogenation and oxidation reactions. Structures of the new metabolites were elucidated by 1-D (H-1, C-13, NOESY), 2-D NMR (DQF-COSY, HMBC, HMQC, NOESY) and HR-MS analyses. (C) 2015 Elsevier B.V. All rights reserved.
dc.identifier.doi10.1016/j.molcatb.2015.01.013
dc.identifier.eissn1873-3158
dc.identifier.issn1381-1177
dc.identifier.urihttps://hdl.handle.net/11424/238300
dc.identifier.wosWOS:000353599300005
dc.language.isoeng
dc.publisherELSEVIER
dc.relation.ispartofJOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAstragalus
dc.subjectMicrobial transformation
dc.subjectCycloastragenol
dc.subjectCyclocanthogenol
dc.subjectAstragenol
dc.subjectBIOTRANSFORMATION
dc.subjectACID
dc.subjectCYCLOASTRAGENOL
dc.subjectTRITERPENOIDS
dc.titleMicrobial transformation of Astragalus sapogenins using Cunninghamella blakesleeana NRRL 1369 and Glomerella fusarioides ATCC 9552
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage34
oaire.citation.startPage29
oaire.citation.titleJOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC
oaire.citation.volume115

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