Publication: Prematüre retinopatisi tespit edilen bebeklerde eşik hastalık gelişiminde etkili risk faktörleri
Abstract
Amaç: Prematüre retinopatisi (PR) tespit edilen bebeklerde eşik hastalık gelişiminde rol oynayan risk faktörlerinin belirlenmesi Yöntem : Kliniğimizde PR ile takip edilen 143 bebeğin eşik hastalığı gelişimi ile ilişkili olduğu düşünülen risk faktörleri incelendi. Hastalara tam oftalmolojik muayene yapıldı. Sonuçlar : PR saptanan 143 bebeğin 39´unda (%27.3) eşik hastalık geliştiği görüldü.Tek değişkenli analizde oksijen tedavisi ve süresinin. yüksek oksijen tedavisi ve süresinin. düşük doğum ağırlığı ve haftasının. aneminin. ventilasyon ve kan transfüzyonu tedavisinin PR riskini arttırdığı saptandı. Çok değişkenli en önemli analizde düşük doğum haftasının PR gelişimi için en önemli risk faktörü olduğu görüldü. Tartışma : Eşik hastalık PR´nin tedavi ile körlükle sonuçlanabilecek en önemli sonucunun önlenebildiği hastalık evresidir. Bu nedenle eşik hastalık oluşumunda etkili olabilecek risk faktörlerinin belirlenmesi ve uygun tarama protokollerinin oluşturulması gerekmektedir.
Purpose: To determine the incidence and risc factors that is associated with development of threshold disease in infants with retinopathy of prematurity (ROP). Methods : 134 infants with ROP in our clinic were evaluated for to determine risc factors that were associated with threshold disease. Complete ophthalmologic examination was done to all babies. Results : Threshold disease were detected in 143 (%27.3) infants. In univariate analysis for threshold disease. oxygen treatment. duration of supplemental oxygen. gestational age. birth weight. blood transfusion. anemia. mechanical ventilation and its duration were associated with increased incidence of threshold disease in infants with ROP. However. in multiple logistic regression analyses gestational age was most important factor for development of threshold disease. Conclusion : Threshold disease is the clinical grade of ROP which with treatment can avoid visual impairment and blindness. Thats why we had to determine the risc factors that were associated with threshold disease.
Purpose: To determine the incidence and risc factors that is associated with development of threshold disease in infants with retinopathy of prematurity (ROP). Methods : 134 infants with ROP in our clinic were evaluated for to determine risc factors that were associated with threshold disease. Complete ophthalmologic examination was done to all babies. Results : Threshold disease were detected in 143 (%27.3) infants. In univariate analysis for threshold disease. oxygen treatment. duration of supplemental oxygen. gestational age. birth weight. blood transfusion. anemia. mechanical ventilation and its duration were associated with increased incidence of threshold disease in infants with ROP. However. in multiple logistic regression analyses gestational age was most important factor for development of threshold disease. Conclusion : Threshold disease is the clinical grade of ROP which with treatment can avoid visual impairment and blindness. Thats why we had to determine the risc factors that were associated with threshold disease.