Publication: In vitro effect of amikacin, imipenem, cefodizime, IFN alpha-2a alone and combinations of antibiotics with IFN alpha-2a on polymorphonuclear leukocyte function in chronic hepatitis patients
| dc.contributor.author | SOYOĞUL GÜRER, ÜMRAN | |
| dc.contributor.authors | Adalati, R; Gurer, US; Cevikbas, A; Johansson, C | |
| dc.date.accessioned | 2022-03-12T17:00:23Z | |
| dc.date.accessioned | 2026-01-11T05:59:20Z | |
| dc.date.available | 2022-03-12T17:00:23Z | |
| dc.date.issued | 2001 | |
| dc.description.abstract | The in vitro effect of amikacin (8 mug/ml), imipenem (30 mug/ml), cefodizime (10 mug/ml), interferon alpha -2a (IFN alpha -2a) (10 IU/ml) and antibiotic combinations with IFNa-2a on polymorphonuclear leukocyte (PMN) functions (phagocytosis and intracellular killing of Candida albicans blastospores) was investigated in chronic hepatitis B patients. Phagocytosis and candidacidal activity was not affected after pretreatment of PMNs with amikacin and imipenem (p > 0.05). Phagocytic activity was enhanced after pretreatment of PMNs with cefodizime and IFN alpha -2a compared with that of control PMNs (p < 0.05), but candidacidal activity was not affected by the same drugs (p > 0.05). Phagocytic and intracellular activity of PMNs were not affected by combinations of IFN alpha -2a and antibiotics (p > 0.05). Copyright (C) 2001 S. Ka rger AG, Baser. | |
| dc.identifier.doi | 10.1159/000048532 | |
| dc.identifier.issn | 0009-3157 | |
| dc.identifier.pubmed | 11399862 | |
| dc.identifier.uri | https://hdl.handle.net/11424/227299 | |
| dc.identifier.wos | WOS:000169068800005 | |
| dc.language.iso | eng | |
| dc.publisher | KARGER | |
| dc.relation.ispartof | CHEMOTHERAPY | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | amikacin | |
| dc.subject | imipenem | |
| dc.subject | cefodizime | |
| dc.subject | IFN alpha-2a | |
| dc.subject | polymorphonuclear leukocyte functions | |
| dc.subject | chronic hepatitis B patients | |
| dc.title | In vitro effect of amikacin, imipenem, cefodizime, IFN alpha-2a alone and combinations of antibiotics with IFN alpha-2a on polymorphonuclear leukocyte function in chronic hepatitis patients | |
| dc.type | article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 265 | |
| oaire.citation.issue | 4 | |
| oaire.citation.startPage | 261 | |
| oaire.citation.title | CHEMOTHERAPY | |
| oaire.citation.volume | 47 |