Publication:
FLUORODENSITOMETRIC DETERMINATION OF BACLOFEN

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dc.contributor.authorsERSOY, L
dc.date.accessioned2022-03-12T16:55:59Z
dc.date.accessioned2026-01-10T21:45:48Z
dc.date.available2022-03-12T16:55:59Z
dc.date.issued1990
dc.description.abstractA fluorodensitometric method was developed for the determination of baclofen. The method is based on the reaction of baclofen with 4-chloro-7-nitrobenzofurazan and measurement of the fluoresence intensity at 540 nm after chromatographic separation on a silica-gel plate. A linear relationship was found between relative fluorescence intensity and concentration over the range 4-100 ng of baclofen per spot. The detection and determination limits are 0.4 and 4.0 ng of baclofen per spot, respectively. The method was applied to human plasma. The recovery of baclofen from plasma was 96.67%.
dc.identifier.doi10.1039/an9901501559
dc.identifier.issn0003-2654
dc.identifier.pubmed2080807
dc.identifier.urihttps://hdl.handle.net/11424/226626
dc.identifier.wosWOS:A1990ER00400009
dc.language.isoeng
dc.publisherROYAL SOC CHEMISTRY
dc.relation.ispartofANALYST
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectBACLOFEN DETERMINATION
dc.subjectBACLOFEN-4-CHLORO-7-NITROBENZOFURAZAN DERIVATIVE
dc.subjectFLUORODENSITOMETRIC DETERMINATION
dc.subjectGAMMA-AMINO-BETA-(PARA-CHLOROPHENYL)BUTYRIC ACID
dc.subjectORTHO-PHTHALDIALDEHYDE
dc.subjectLIQUID-CHROMATOGRAPHY
dc.subjectURINE
dc.subjectDERIVATIZATION
dc.subjectPLASMA
dc.titleFLUORODENSITOMETRIC DETERMINATION OF BACLOFEN
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage1560
oaire.citation.issue12
oaire.citation.startPage1559
oaire.citation.titleANALYST
oaire.citation.volume115

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