Publication: Genel cerrahi servisinde yatan hastalarda ilaç kullanımının değerlendirilmesi
Abstract
Amaç: Perioperatif eczacılık, cerrahi müdahale sürecinde hasta odaklı tedavide akılcı ilaç kullanımını sağlayarak tedavinin en uygun şekilde uygulanmasına yardımcı olur. Çalışmamızda genel cerrahi servisinde yatan hastalarda ilaç kullanımının değerlendirilmesi amaçlanmıştır. Gereç ve Yöntem: Prospektif tanımlayıcı nitelikte olan çalışmamız İstanbul'daki üçüncü basamak bir eğitim-araştırma hastanesinin genel cerrahi kliniğinde Ocak 2022-Temmuz 2022 tarihleri arasında yürütülmüştür. Herhangi bir cerrahi işlem için hastaneye yatırılan ve cerrahi sonrası hastanede yatan hastalar çalışmaya dahil edilmiştir. Hastaların sosyodemografik özellikleri, cerrahi öncesi ve sonrası ilaç tedavileri kaydedilmiştir. Potansiyel ilaç etkileşimleri Lexicomp veritabanında değerlendirilmiştir. Bulgular: Çalışmaya alınan 95 hastanın yaş ortalaması 54 (19-86) olup, %56,8’i kadın hastalardan oluşmaktadır. Hastaların %66,3’ünün en az bir kronik hastalığı olduğu tespit edilmiştir. Hastaların %70,5’inde en az bir adet cerrahi öykü olduğu gözlenmiştir. Cerrahi sonrası dönemde kullanılan ilaç sayısının cerrahi öncesi döneme göre daha fazla olduğu saptanmıştır (5,7 ve 4,5), p<0.0001). Cerrahi sonrası doktor istemlerinde tespit edilen potansiyel ilaç etkileşim sayısının, cerrahi öncesine göre daha fazla olduğu tespit edilmiştir (p<0,05). Sonuç: Çalışmamızda cerrahi operasyon planlanan hastaların büyük çoğunluğunda en az bir kronik hastalık mevcuttur. Cerrahi sonrası dönemde kullanılan ilaç sayısının fazla olmasının potansiyel ilaç etkileşimine neden olabileceğini düşünmekteyiz. Cerrahi kliniğinde akılcı ve güvenli ilaç kullanımının klinik eczacılık hizmetleri ile sağlanacağına inanmaktayız.
Objective: Perioperative pharmacy optimizes medical treatment by providing rational drug use in patient-focused therapy during the surgical intervention. In our study, it was aimed to evaluate the use of medication and patient profiles in the general surgery service. Materials and Methods: This study is a prospective descriptive study, planned and conducted in the general surgery clinic of a tertiary care training-research hospital in Istanbul between January 2022-July 2022. Patients hospitalized for any surgical procedure and postoperatively hospitalized were included in the study. Sociodemographic characteristics of the patients and pre-post operative drug treatments were recorded. Potential drug interactions were evaluated via Lexicomp database. Results: The mean age of the 95 patients included in the study was 54 (19-86) and 56,8% were female. It was determined that %66,3 of the patients had at least one chronic disease. It was determined that the number of medications used in the postoperative period was higher than in the preoperative period (5.7 vs 4.5, p<0.0001). It was determined that the number of potential drug interactions detected in the doctor's orders after surgery was higher than before the surgery (p<0.05). Conclusion: In our study, most of the patients who were planned for surgery had at least one chronic disease. We think that the high number of medications used in the postoperative period may cause potential drug interactions. We believe that clinical pharmacy services will provide rational and safe medication use in the surgery clinic.
Objective: Perioperative pharmacy optimizes medical treatment by providing rational drug use in patient-focused therapy during the surgical intervention. In our study, it was aimed to evaluate the use of medication and patient profiles in the general surgery service. Materials and Methods: This study is a prospective descriptive study, planned and conducted in the general surgery clinic of a tertiary care training-research hospital in Istanbul between January 2022-July 2022. Patients hospitalized for any surgical procedure and postoperatively hospitalized were included in the study. Sociodemographic characteristics of the patients and pre-post operative drug treatments were recorded. Potential drug interactions were evaluated via Lexicomp database. Results: The mean age of the 95 patients included in the study was 54 (19-86) and 56,8% were female. It was determined that %66,3 of the patients had at least one chronic disease. It was determined that the number of medications used in the postoperative period was higher than in the preoperative period (5.7 vs 4.5, p<0.0001). It was determined that the number of potential drug interactions detected in the doctor's orders after surgery was higher than before the surgery (p<0.05). Conclusion: In our study, most of the patients who were planned for surgery had at least one chronic disease. We think that the high number of medications used in the postoperative period may cause potential drug interactions. We believe that clinical pharmacy services will provide rational and safe medication use in the surgery clinic.