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Synthesis and antimicrobial activity of some new hydrazones of 4-fluorobenzoic acid hydrazide and 3-acetyl-2,5-disubstituted-1,3,4-oxadiazolines

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dc.contributor.authorsRollas, S; Gulerman, N; Erdeniz, H
dc.date.accessioned2022-03-12T17:00:34Z
dc.date.accessioned2026-01-11T07:08:21Z
dc.date.available2022-03-12T17:00:34Z
dc.date.issued2002
dc.description.abstractA series of hydrazide hydrazones and 1,3,4-oxadiazolines of 4-fluorobenzoic acid hydrazide were prepared and evaluated as potential antimicrobial agents and were tested for their antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans. From these compounds, 4-fluorobenzoic acid[(5-nitro-2-furanyl)methylene]hydrazide (1a) showed equal activity with ceftriaxone against S. aureus. In addition, the MIC values of compounds 1c, 1d and 2a for the same strain were in the range of those reported for ceftriaxone according to NCCLS 1997. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
dc.identifier.doi10.1016/S0014-827X(01)01192-2
dc.identifier.issn0014-827X
dc.identifier.pubmed11902660
dc.identifier.urihttps://hdl.handle.net/11424/227318
dc.identifier.wosWOS:000177619500012
dc.language.isoeng
dc.publisherELSEVIER SCIENCE SA
dc.relation.ispartofFARMACO
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectantimicrobial activity
dc.subjecthydrazones
dc.subject4-fluorobenzoic acid hydrazide
dc.subjectDERIVATIVES
dc.titleSynthesis and antimicrobial activity of some new hydrazones of 4-fluorobenzoic acid hydrazide and 3-acetyl-2,5-disubstituted-1,3,4-oxadiazolines
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage174
oaire.citation.issue2
oaire.citation.startPage171
oaire.citation.titleFARMACO
oaire.citation.volume57

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