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Medicinal Chemistry and Anti-Inflammatory Activity of Nitric Oxide-Releasing NSAI Drugs

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dc.contributor.authorKÜÇÜKGÜZEL, ŞÜKRİYE GÜNİZ
dc.contributor.authorsKoc, Esra; Kucukguzel, S. Guniz
dc.date.accessioned2022-03-10T15:25:04Z
dc.date.accessioned2026-01-11T13:44:10Z
dc.date.available2022-03-10T15:25:04Z
dc.date.issued2009
dc.description.abstractNitric Oxide, which acts as a non-specific cytotoxic mediator and a biological messenger on immunological competence, has been gaining significantly increasing importance. As an alternative to conventional NSAIDs having significant side effects, pharmacologically improved and therapeutically enhanced NO releasing non-steroidal anti-inflammatory drugs with less side effects are being planned to produce.
dc.identifier.doi10.2174/138955709788167556
dc.identifier.eissn1875-5607
dc.identifier.issn1389-5575
dc.identifier.pubmed19456291
dc.identifier.urihttps://hdl.handle.net/11424/220092
dc.identifier.wosWOS:000265799300009
dc.language.isoeng
dc.publisherBENTHAM SCIENCE PUBL LTD
dc.relation.ispartofMINI-REVIEWS IN MEDICINAL CHEMISTRY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectNitric oxide
dc.subjectNO-NSAID
dc.subjectanti-inflammatory
dc.subjectPROOF-OF-CONCEPT
dc.subjectINDOMETHACIN DERIVATIVES
dc.subjectGASTROINTESTINAL SAFETY
dc.subjectNITROASPIRIN NCX-4016
dc.subjectACID-DERIVATIVES
dc.subjectCYCLOOXYGENASE-2
dc.subjectAGENTS
dc.subjectASPIRIN
dc.subjectDESIGN
dc.subject5-LIPOXYGENASE
dc.titleMedicinal Chemistry and Anti-Inflammatory Activity of Nitric Oxide-Releasing NSAI Drugs
dc.typereview
dspace.entity.typePublication
oaire.citation.endPage619
oaire.citation.issue5
oaire.citation.startPage611
oaire.citation.titleMINI-REVIEWS IN MEDICINAL CHEMISTRY
oaire.citation.volume9

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