Publication:
DETERMINATION OF METOPROLOL TARTRATE BY ION-PAIR EXTRACTION WITH BROMOTHYMOL BLUE

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VCH PUBLISHERS INC

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This paper reports a simple and sensitive spectrophotometric method for the determination of metoprolol tartrate in tablets. The method involves the formation of an ion-pair between the drug and bromothymol blue and after extraction with dichloromethane, measuring its absorbance.

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