A case of epulis granulomatosa with clinical and radiological findings resembling langerhans cell histiocytosis

Abstract

Aim Langerhans cell histiocytosis (LCH) is a rare disease characterized by the proliferation of Langerhans cells. The differential diagnosis of LCH from epulis granulomatosa may be more difficult, given that the major symptoms of LCH are swelling and a floating tooth appearance. The purpose of this study was to provide a case of epulis granulomatosa that resembled LCH in the jaw bones based on clinical and radiological symptoms, as well as to warn against the possibility of misdiagnosis. Case Report Smooth-surfaced, lobular, erythematous, sessile, and fibrotic tissue hyperplasias were seen in the maxilla anterior edentulous area and the mandible’s left posterior region. The patient’s radiographic findings revealed extensive alveolar bone destruction in the maxilla and mandible, as well as severe bone destruction in the posterior area of the left mandible, consistent with a floating tooth. Under local anesthetic, an excisional biopsy of the lesion was performed in the left posterior region of the mandible. Histopathological examination revealed that the patient had inflammatory fibrous tissue hyperplasia. Discussion The clinical symptoms of LCH patients vary depending on their location and degree of involvement. When completing a full mouth examination on a patient, it is critical to detect soft tissue abnormalities as well as provide an accurate diagnosis and treatment plan. Conclusion LCH, together with surrounding inflammatory alterations, should be considered in the differential diagnosis of osteolytic lesions of the jaw