Publication: Fibromiyalji sendromlu hastalarda klinik belirtilerin sıklığı ve fibromiyalji sendromu-hipermobilite ilişkisi
Abstract
Bu çalışmada fibromiyalji sendromu (FS) olan hastalarda hipermobilite varlığını ve klinik belirtilerin sıklığını saptamayı amaçladık. Polikliniğimize başvuran, 1990 Amerikan Romatizma Birliği kriterlerine göre FS tanısı almış yaş ortalaması 42,6±9,7 yıl olan 52 kadın çalışmaya dahil edildi. Hastalar sosyoekonomik durumları, ağrı ve diğer sistem yakınmaları açısından sorgulandı. Ağrı şiddeti görsel analog skala (GAS) ile, hipermobilite varlığı ise Beighton hipermobilite kriterlerine göre değerlendirildi. Hastaların %67,3’ü evli, %50’si ev hanımı olup, %75’nin ekonomik seviyesi orta idi. Ortalama eğitim süresi 8,8±4,8 yıl, ağrı süresi 4,9±4,6 yıl, GAS 7,2±1,7 cm idi. Sistem sorgulamasında hastaların %96,2’sinde yorgunluk, %76,9’unda sabah tutukluğu, %69,2’sinde uyku bozukluğu mevcuttu. Pearson lineer korelasyon analizi yapıldığında; GAS ile ekonomik durum arasında negatif korelasyon olduğu saptandı (r=-0,32; p=0,021). Medeni hali bekar olan FS’li hastalarda yorgunluk daha fazla bulundu. Ortalama Beighton total skoru 5,4±2 (0-9) idi. Hastaların %81,4’ünde Beighton total skoru ≥5 olup, bu da hipermobilite lehine idi. Beighton total skoru ile yaş arasında negatif korelasyon saptandı (r=-0,45; p=0,02). Sonuç olarak, FS’li hastalarda benign hipermobilite olabileceği akılda bulundurulmalıdır.
In this study, the objective was to evaluate the presence of hypermobility and the frequency of clinical signs in patients with fibromyalgia syndrome (FS). Fifty two women with a mean age of 42.6±9.7 years who had diagnosis of FS according to American College of Rheumatology criteria, were included in the study. The patients were questioned according to social and economical status, pain and other systemic complaints. Pain level was evaluated by visual analog scale (VAS) and hypermobility by using Beighton hypermobility criteria. 67.3% of the patients were married, 50% were housewife, and 75% women’s economical level was medium. Mean duration of education and pain were 8.8±4.8 and 4.9±4.6 years, respectively. Mean VAS score was 7.2±1.7 cm. In the systemic evaluation, 96.2% of patients had fatigue, 76.9% had morning stiffness, and 69.2% had sleep disorder. In the Pearson linear correlation analysis; there was a negative correlation between VAS and economical level (r=-0.32; p=0.021). Unmarried FS patients had higher ratio of fatigue than others. Mean Beighton total score was 5.4±2.03 (0-9). In 81.4% of patients Beighton total score was ≥5 which could be interpreted as an association with hypermobility. We found a negative correlation between Beighton total score and age (r=-0.45; p=0.02). As a result, it should be kept in mind that a majority of FS patients could have benign hypermobility.
In this study, the objective was to evaluate the presence of hypermobility and the frequency of clinical signs in patients with fibromyalgia syndrome (FS). Fifty two women with a mean age of 42.6±9.7 years who had diagnosis of FS according to American College of Rheumatology criteria, were included in the study. The patients were questioned according to social and economical status, pain and other systemic complaints. Pain level was evaluated by visual analog scale (VAS) and hypermobility by using Beighton hypermobility criteria. 67.3% of the patients were married, 50% were housewife, and 75% women’s economical level was medium. Mean duration of education and pain were 8.8±4.8 and 4.9±4.6 years, respectively. Mean VAS score was 7.2±1.7 cm. In the systemic evaluation, 96.2% of patients had fatigue, 76.9% had morning stiffness, and 69.2% had sleep disorder. In the Pearson linear correlation analysis; there was a negative correlation between VAS and economical level (r=-0.32; p=0.021). Unmarried FS patients had higher ratio of fatigue than others. Mean Beighton total score was 5.4±2.03 (0-9). In 81.4% of patients Beighton total score was ≥5 which could be interpreted as an association with hypermobility. We found a negative correlation between Beighton total score and age (r=-0.45; p=0.02). As a result, it should be kept in mind that a majority of FS patients could have benign hypermobility.