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Chemical characterization and pharmacological profile of tribulus terrestris extracts: A novel source of cosmeceuticals and pharmaceuticals

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dc.contributor.authorŞENKARDEŞ, İSMAİL
dc.contributor.authorsUYSAL Ş., ŞENKARDEŞ İ., Jekő J., Cziáky Z., Zengin G.
dc.date.accessioned2023-02-07T07:56:32Z
dc.date.accessioned2026-01-10T18:33:00Z
dc.date.available2023-02-07T07:56:32Z
dc.date.issued2023-04-01
dc.description.abstract© 2023 Elsevier LtdTribulus terrestris is widely used in traditional medicine and in dietary supplements. Therefore, this research aims to obtain comprehensive information on antioxidant properties, enzyme inhibitory activity and chemical composition of T. terrestris leaves. HPLC-MS/MS was used to further extensively characterize the chemical composition of T. terrestris extracts. 27, 75, and 51 chemical components were identifed in ethyl acetate, methanol and water extract, respectively. The radical scavenging activity results showed that water extract had the strongest acvitiy (DPPH: 30.50 mgTE/g, ABTS: 44.49 mgTE/g). The reducing power activity was assessed by FRAP and CUPRAC assays. The highest CUPRAC activity is shown by the ethyl acetate extract (79.01 mgTE/g). Water extract showed the highest metal chelating activity compared with other extract. In general, the highest antioxidant capacity were obtained in the water extract. Ethyl acetate extract exhibited the highest enzyme inhibition activity (AChE: 1.56 mgGAE/g; BChE: 2.14 mgGALAE/g; α-amylase: 0.73 mmolACE/g; Tyrosinase: 30.14 mgKAE/g) compared with other extracts. This research provides a scientific basis for the development of natural antioxidant and enzyme inhibiton sources from T. terrestris.
dc.identifier.citationUYSAL Ş., ŞENKARDEŞ İ., Jekő J., Cziáky Z., Zengin G., "Chemical characterization and pharmacological profile of Tribulus terrestris extracts: A novel source of cosmeceuticals and pharmaceuticals", Biochemical Systematics and Ecology, cilt.107, 2023
dc.identifier.doi10.1016/j.bse.2023.104600
dc.identifier.issn0305-1978
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85146904083&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/286028
dc.identifier.volume107
dc.language.isoeng
dc.relation.ispartofBiochemical Systematics and Ecology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTarımsal Bilimler
dc.subjectÇevre Mühendisliği
dc.subjectÇevre Teknolojisi
dc.subjectEkoloji ve Kirlenme
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSitogenetik
dc.subjectTemel Bilimler
dc.subjectMühendislik ve Teknoloji
dc.subjectAgricultural Sciences
dc.subjectEnvironmental Engineering
dc.subjectEnvironmental Technology
dc.subjectEcology and Pollution
dc.subjectLife Sciences
dc.subjectMolecular Biology and Genetics
dc.subjectCytogenetic
dc.subjectNatural Sciences
dc.subjectEngineering and Technology
dc.subjectTarım ve Çevre Bilimleri (AGE)
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectÇevre / Ekoloji
dc.subjectEKOLOJİ
dc.subjectBİYOKİMYA VE MOLEKÜLER BİYOLOJİ
dc.subjectAgriculture & Environment Sciences (AGE)
dc.subjectLife Sciences (LIFE)
dc.subjectENVIRONMENT/ECOLOGY
dc.subjectMOLECULAR BIOLOGY & GENETICS
dc.subjectECOLOGY
dc.subjectBIOCHEMISTRY & MOLECULAR BIOLOGY
dc.subjectEkoloji, Evrim, Davranış ve Sistematik
dc.subjectBiyokimya
dc.subjectEcology, Evolution, Behavior and Systematics
dc.subjectBiochemistry
dc.subjectAntioxidant
dc.subjectChemical compositions
dc.subjectEnzyme inhibition
dc.subjectT. terrestris
dc.titleChemical characterization and pharmacological profile of tribulus terrestris extracts: A novel source of cosmeceuticals and pharmaceuticals
dc.typearticle
dspace.entity.typePublication

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