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Surgery and outcome of infective endocarditis in octogenarians: Prospective data from the ESC EORP EURO-ENDO registry

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Purpose High mortality and a limited performance of valvular surgery are typical features of infective endocarditis (IE) in octogenarians, even though surgical treatment is a major determinant of a successful outcome in IE. Methods Data from the prospective multicentre ESC EORP EURO-ENDO registry were used to assess the prognostic role of valvular surgery depending on age. Results As compared to = 80 yo had lower rates of theoretical indication for valvular surgery (49.1% vs. 60.3%, p = 80 yo were matched to 608 = 80 yo. Overall mortality remained higher in >= 80 yo (in-hospital: HR 1.50[1.06-2.13], p = 0.0210; 1-yr: HR 1.58[1.21-2.05], p = 0.0006), but was not different from that of = 80 yo patients than in = 80 yo is similar to = 80 yo patients.

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Pazdernik M., Iung B., MUTLU B., Alla F., Riezebos R., Kong W., Pereira Nunes M. C., Pierard L., Srdanovic I., Yamada H., et al., "Surgery and outcome of infective endocarditis in octogenarians: prospective data from the ESC EORP EURO-ENDO registry", INFECTION, cilt.50, sa.5, ss.1191-1202, 2022

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