Publication: Spinonin, a novel glycoside from Ononis spinosa subsp leiosperma
| dc.contributor.authors | Kirmizigul, S; Goren, N; Yang, SW; Cordell, GA; BozokJohansson, C | |
| dc.date.accessioned | 2022-03-12T16:57:48Z | |
| dc.date.accessioned | 2026-01-11T11:07:06Z | |
| dc.date.available | 2022-03-12T16:57:48Z | |
| dc.date.issued | 1997 | |
| dc.description.abstract | The roots of Ononis spinosa subsp. leiosperma (Leguminosae) afforded a new glycoside, spinonin (1), possessing a novel skeleton, in addition to the known isoflavonoid glycoside, ononin [7 beta-(glucosyloxy)formononetin] (2) and the known pterocarpan, 7-demethoxy-7-D-(glucosyloxy)-homopterocarpin (3). The structure of the new isolate was elucidated by spectral methods including H-1 and C-13 NMR, COSY, APT, HETCOR, HMBC, NOESY, CD, FABMS, HRMS, EIMS, CIMS, and some chemical reactions. Spinonin was inactive against a number of human cancer cell Lines and HIV-1 reverse transcriptase. The compounds 1 and 3 showed weak activity against Pseudomonas aeruginosa, whereas 2 was active against beta-hemolytic Streptococcus. | |
| dc.identifier.doi | 10.1021/np9605652 | |
| dc.identifier.issn | 0163-3864 | |
| dc.identifier.pubmed | 9182126 | |
| dc.identifier.uri | https://hdl.handle.net/11424/226976 | |
| dc.identifier.wos | WOS:A1997WW00600012 | |
| dc.language.iso | eng | |
| dc.publisher | AMER CHEMICAL SOC | |
| dc.relation.ispartof | JOURNAL OF NATURAL PRODUCTS | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | RESORCINOL DERIVATIVES | |
| dc.subject | ALKYLRESORCINOLS | |
| dc.subject | COMPONENTS | |
| dc.subject | VISCOSA | |
| dc.subject | NATRIX | |
| dc.title | Spinonin, a novel glycoside from Ononis spinosa subsp leiosperma | |
| dc.type | article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 381 | |
| oaire.citation.issue | 4 | |
| oaire.citation.startPage | 378 | |
| oaire.citation.title | JOURNAL OF NATURAL PRODUCTS | |
| oaire.citation.volume | 60 |