Publication:
Monitoring of mycophenolic acid in the plasma of transplant patients by capillary electrophoresis

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dc.contributor.authorsUensalan, S.; Hempel, G.; Fobker, M.; Wuerthwein, G.; Boos, J.
dc.date.accessioned2022-03-12T17:21:04Z
dc.date.accessioned2026-01-11T19:02:39Z
dc.date.available2022-03-12T17:21:04Z
dc.date.issued2006
dc.description.abstractPlasma samples from 60 transplant patients on mycophenolate mofetil therapy were analysed using validated capillary electrophoresis (CE) method to determine mycophenolic acid (MPA) and its main metabolite mycophenolic acid glucuronide. Enzyme multiplied immunoassay technique (EMIT) values were available for the same samples. The differences between the results from the two methods was clarified by using Bland-Altman analysis and further statistical analysis. More than 90% of the results showed a positive bias, with EMIT giving higher levels than CE.
dc.identifier.doi10.1365/s10337-006-0046-0
dc.identifier.eissn1612-1112
dc.identifier.issn0009-5893
dc.identifier.urihttps://hdl.handle.net/11424/228309
dc.identifier.wosWOS:000241507600007
dc.language.isoeng
dc.publisherSPRINGER HEIDELBERG
dc.relation.ispartofCHROMATOGRAPHIA
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectcapillary electrophoresis
dc.subjectenzyme multiplied immunoossay
dc.subjectmycophenolic acid
dc.subjectTANDEM MASS-SPECTROMETRY
dc.subjectLIQUID-CHROMATOGRAPHY
dc.subjectGLUCURONIDE METABOLITE
dc.subjectRECIPIENTS
dc.subjectMOFETIL
dc.subjectEMIT
dc.subjectIMMUNOASSAY
dc.subjectHPLC
dc.subjectPHARMACOKINETICS
dc.subjectIDENTIFICATION
dc.titleMonitoring of mycophenolic acid in the plasma of transplant patients by capillary electrophoresis
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage421
oaire.citation.issue7-8
oaire.citation.startPage419
oaire.citation.titleCHROMATOGRAPHIA
oaire.citation.volume64

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