Publication:
Absorption of ethyl 2-cyanoacrylate tissue adhesive

dc.contributor.authorsKaplan, M; Oral, B; Rollas, S; Kut, MS; Demirtas, MM
dc.date.accessioned2022-03-12T17:17:07Z
dc.date.accessioned2026-01-11T17:19:38Z
dc.date.available2022-03-12T17:17:07Z
dc.date.issued2004
dc.description.abstractThe aim of this study was to investigate absorption of ethyl 2-cyanoacrylate glue when used as a tissue adhesive. Ethyl 2-cyanoacrylate was applied subcutaneously to four rats; its presence in blood and urine was investigated by using High Pressure Liquid Chromatography. Blood samples were drawn at baseline and after 2, 4, 6, 24, 48, 54, 78, 96 hours following application. Urine samples were obtained at baseline and after 4, 24, 48, 72, 96 hours. Administration of ethyl 2-cyanoacrylate resulted in its absorption of unchanged ethyl 2-cyanoacrylate and unknown metabolites, in plasma and urine.
dc.identifier.doi10.1007/BF03190579
dc.identifier.issn0378-7966
dc.identifier.pubmed15230333
dc.identifier.urihttps://hdl.handle.net/11424/227771
dc.identifier.wosWOS:000222143300001
dc.language.isoeng
dc.publisherMEDECINE ET HYGIENE
dc.relation.ispartofEUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectethyl 2-cyanoacrylate
dc.subjecttissue adhesive
dc.subjecthigh pressure liquid chromatography analysis
dc.subjectIDENTIFICATION
dc.subjectMETABOLISM
dc.subjectACID
dc.subjectRATS
dc.titleAbsorption of ethyl 2-cyanoacrylate tissue adhesive
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage81
oaire.citation.issue2
oaire.citation.startPage77
oaire.citation.titleEUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
oaire.citation.volume29

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