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The use of 18F-FDG PET ratios in the differential diagnosis of common malignant brain tumors

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2015

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ELSEVIER SCIENCE INC

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Abstract

Objective: This study examined the use of positron emission tomography (PET) ratios to improve the diagnostic ability of 18F-FDG PET/computed tomography (CT) in the differentiation of enhancing brain metastases, central nervous system lymphomas, and gliomas. Materials and methods: Seventy-six patients with malignant brain tumors and available magnetic resonance imaging and PET/CT examinations were included. Results: Among standardized uptake value (SUV)-related parameters tested, tumor maximum SUV to ipsilateral cortex maximum SUV ratio (Tmax:WMimax) and maximum SUV (SUVmax) proved to be the two most valuable parameters for differential diagnosis. Conclusion: in addition to SUVmax,Tmax:WMimax also seems to provide helpful information for the differential diagnosis of lymphomas from other malignant brain tumors. (C) 2015 Elsevier Inc. All rights reserved.

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18F-FDG positron emission tomography, Differential diagnosis, Brain metastasis, Glioma, Central nervous system lymphoma, POSITRON-EMISSION-TOMOGRAPHY, NERVOUS-SYSTEM LYMPHOMA, RADIATION NECROSIS, F-18-FDG PET, FDG-PET, C-11-METHIONINE PET, GRADE, RECURRENCE, PERFUSION, GLIOMAS

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https://hdl.handle.net/11424/233550

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