Publication: EFFECT OF ADDITIVES ON DISSOLUTION CHARACTERISTICS OF FUROSEMIDE-POLYVINYLPYRROLIDONE SOLID-DISPERSION SYSTEMS
| dc.contributor.authors | AKBUGA, J | |
| dc.date.accessioned | 2022-03-12T16:55:42Z | |
| dc.date.accessioned | 2026-01-11T09:01:12Z | |
| dc.date.available | 2022-03-12T16:55:42Z | |
| dc.date.issued | 1991 | |
| dc.description.abstract | The effect of additive type and concentration on drug dissolution from furosemide: PVP solid-dispersion systems has been studied. Avicel PH101, Ac-Di-Sol, Primojel, Kollidon CL and Aerosil were examined as additives. Two different drugs: PVP ratios (1:2 and 1:6) were used and additives were added in low and high concentrations (2 % and 20 %). Furosemide-PVP solid dispersion systems are sensitive to the incorporation of additives. Kollidon CL is the best additive for furosemide-PVP solid-dispersion systems. A retardant effect was observed by the addition of Ac-Di-Sol. Furthermore, the effect of Avicel PH101, Primojel and Aerosil depends on furosemide: PVP ratio and also concentration of additives. | |
| dc.identifier.doi | doiWOS:A1991GK33300004 | |
| dc.identifier.issn | 0031-711X | |
| dc.identifier.uri | https://hdl.handle.net/11424/226502 | |
| dc.identifier.wos | WOS:A1991GK33300004 | |
| dc.language.iso | eng | |
| dc.publisher | ECV-EDITIO CANTOR VERLAG MEDIZIN NATURWISSENSCHAFTEN | |
| dc.relation.ispartof | PHARMAZEUTISCHE INDUSTRIE | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | DIURETICS | |
| dc.subject | FUROSEMIDE-PVP, DISSOLUTION CHARACTERISTICS, EFFECT OF ADDITIVES, | |
| dc.subject | SOLID-DISPERSION | |
| dc.title | EFFECT OF ADDITIVES ON DISSOLUTION CHARACTERISTICS OF FUROSEMIDE-POLYVINYLPYRROLIDONE SOLID-DISPERSION SYSTEMS | |
| dc.type | article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 860 | |
| oaire.citation.issue | 9 | |
| oaire.citation.startPage | 857 | |
| oaire.citation.title | PHARMAZEUTISCHE INDUSTRIE | |
| oaire.citation.volume | 53 |