Publication:
Expression of nm23 and tenascin in invasive ductal carcinomas of the breast

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dc.contributor.authorsKaya, H; Hucumenoglu, S; Bozkurt, SU; Ekicioglu, G; Kotiloglu, E
dc.date.accessioned2022-03-12T17:00:04Z
dc.date.accessioned2026-01-11T06:19:40Z
dc.date.available2022-03-12T17:00:04Z
dc.date.issued2002
dc.description.abstractObjective: In this series of ductal carcinoma of the breast, immunoexpression of antimetastasis gene nm23 and tenascin was examined and the role in prognosis was investigated by correlation with the tumour grade and stage, and ER/PR immunoexpression. Material and Methods: In this Study 27 ductal carcinomas of the breast, ere analysed for expression of tenascin and nm23 antimetastasis genes by immunohistochemistry. Results: The results Of our Study revealed a statistically significant cot-relation between nm23-H1 immunoexpression and lymph node metastasis. We also found a statistically significant correlation between tenascin and nm23-H1 immunoexpression. Our results suggest that tenascin limits tumour spread. Conclusion(s): Antimetastasis gene expression can be used in predicting lymph node metastasis in ductal carcinomas of the breast.
dc.identifier.doidoiWOS:000176196700022
dc.identifier.issn0392-2936
dc.identifier.pubmed12094967
dc.identifier.urihttps://hdl.handle.net/11424/227273
dc.identifier.wosWOS:000176196700022
dc.language.isoeng
dc.publisherI R O G CANADA, INC
dc.relation.ispartofEUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjecttenascin
dc.subjectnm23 expression
dc.subjectductal carcinoma
dc.subjectbreast
dc.subjectCANCER
dc.subjectP53
dc.titleExpression of nm23 and tenascin in invasive ductal carcinomas of the breast
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage+
oaire.citation.issue3
oaire.citation.startPage261
oaire.citation.titleEUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY
oaire.citation.volume23

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