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Swelling and diffusion studies of poly(N-isopropylacrylamide/itaconic acid) copolymeric hydrogels in water and aqueous solutions of drugs

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dc.contributor.authorKAYAMAN APOHAN, NİLHAN
dc.contributor.authorsTasdelen, B; Kayaman-Apohan, N; Guven, O; Baysal, BM
dc.date.accessioned2022-03-12T17:17:47Z
dc.date.accessioned2026-01-10T20:22:24Z
dc.date.available2022-03-12T17:17:47Z
dc.date.issued2004
dc.description.abstractN-Isopropylacrylamide/itaconic acid hydrogels (NIPAAm/IA) containing different amounts of itaconic acid prepared by irradiating with gamma-radiation were used in experiments on swelling and diffusion of the model drugs methylene blue, lidocaine, and sildenafil citrate (VIAGRA). The NIPAAm/IA hydrogels containing 0-3 mol % itaconic acid irradiated at 48 kGy has been used for swelling and diffusion studies in water and aqueous solutions containing the above-mentioned model drugs. For these hydrogels, swelling studies indicated that swelling increased with the following order: water > lidocaine > methylene blue > VIAGRA. Diffusions of water and the drugs within hydrogels were found to be non-Fickian in character. (C) 2003 Wiley Periodicals, Inc. J Appl Polym Sci 91: 911-915, 2004.
dc.identifier.doi10.1002/app.13223
dc.identifier.issn0021-8995
dc.identifier.urihttps://hdl.handle.net/11424/227897
dc.identifier.wosWOS:000186915200030
dc.language.isoeng
dc.publisherJOHN WILEY & SONS INC
dc.relation.ispartofJOURNAL OF APPLIED POLYMER SCIENCE
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjecthydrogels
dc.subjectradiation
dc.subjectdiffusion
dc.subjectPOLYMERS
dc.subjectRELEASE
dc.subjectTRANSPORT
dc.titleSwelling and diffusion studies of poly(N-isopropylacrylamide/itaconic acid) copolymeric hydrogels in water and aqueous solutions of drugs
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage915
oaire.citation.issue2
oaire.citation.startPage911
oaire.citation.titleJOURNAL OF APPLIED POLYMER SCIENCE
oaire.citation.volume91

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