Analytical studies on the antioxidant activity of cordyceps militaris mushroom

Abstract

AbstractFungi are living organisms that do not contain chlorophyll and reproduce as parasites or saprophytes via spores. Cordyceps militaris, a genus of Cordyceps, has been used therapeutically for centuries in traditional Chinese medicine. Cordyceps militaris contains cordycepin, adenosine, cordycepic acid, superoxide dismutase enzyme and cordyceps polysaccharides with biological and pharmacological activities. Cordycepin is a biologically active broad-spectrum nucleoside analogue and was originally derived from Cordyceps militaris. In our study, a review was created by examining the analytical studies on the antioxidant activity of Cordyceps militaris and the determination of the bioactive compounds it contains. In the review study, the antioxidant properties and phenolic components of Cordyceps militaris were obtained by searching the literature with Springer, PubMed, Web of Science, Science Direct and Scopus databases. From the information obtained by various spectrophotometric methods, DPPH(1,1-Diphenyl-2-picrylhydrazil), ABTS•+(2,2`azinobis (3-ethylbenzothiazoline-6-sulfonic) acid), FRAP(iron (III) ion reducing antioxidant power method), Oxygen Radical Absorbance Capacity (ORAC) Method, Hydroxy radical capture activity and Folin-Ciocalteu reagent (FCR), TEAC (Trolox equivalent antioxidant capacity) methods were investigated. Looking at the data, it was determined that Cordyceps militaris contains polysaccharides with important bioactive properties, which are known to be antiviral, antioxidant, anti-inflammatory, antitumor, neuroprotective, antihypertensive and immunomodulatory. These polysaccharides have been proven to have liver-protective, kidney-protective, neuroprotective, immunomodulatory, antidiabetes, anticancer, and antioxidant effects. Many health products in China contain Cordyceps militaris. It is known that drugs produced from the Cordyceps militaris plant are used for kidney, lung health, delaying aging and sleep, regulators. Considering these data, it can be recommended to be used in supportive treatment in medicine under the control of a doctor. Keywords: Cordyceps militaris, Cordycepin, Antioxidant Activity Methods, Bioactive compounds.