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Synthesis, characterization of novel coupling products and 4-arylhydrazono-2-pyrazoline-5-ones as potential antimycobacterial agents

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Date

2002

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ELSEVIER SCIENCE SA

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Abstract

Novel coupling products 7a-d and 4-arylhydrazono-2 pyrazoline-5-ones 8a-e were synthesized and evaluated for antimycobacterial activity against Mycobacterium tuberculosis H37Rv and Mycobacterium avium. Compound 7b was found to be the most potent derivatives of the 7a-d series by an MIC value of 6.25 mug/ml. (C) 2002 Published by Editions scientifiques et medicales Elsevier SAS.

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coupling products, 4-arylhydrazono-2-pyrazoline-5-one, 1,2,4-triazole, hydrazide-hydrazones, DERIVATIVES, ACID

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https://hdl.handle.net/11424/224031

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