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Prognostic significance of necrosis in ampullary carcinomas.

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dc.contributor.authorBAĞCI ÇULÇİ, PELİN
dc.contributor.authorsAkar K. E., Bagci P.
dc.date.accessioned2024-08-12T07:50:44Z
dc.date.accessioned2026-01-11T10:39:58Z
dc.date.available2024-08-12T07:50:44Z
dc.date.issued2024-06-26
dc.description.abstractBackground/aimsNecrosis is an important pathological feature that reflects high malignancy potential in tumors such as hepatocellular carcinoma and renal cell carcinoma. We aimed to elucidate the prognostic impact of necrosis in ampullary carcinomas.Materials and methodsWe reviewed 101 consecutive cases of ampullary carcinoma for tumor necrosis, types of necrosis, macroscopic and microscopic histopathological subtypes, lymphatic-vascular-perineural invasions, and other histopathological parameters.ResultsTumor necrosis was present in 19 (18.8%) cases and was identified as an independent poor prognostic indicator in multivariate survival analysis (p = 0.029).ConclusionThe presence of necrosis in ampullary carcinomas is directly related to vascular and perineural invasion and is a poor prognostic indicator independent of tumor stage. Including the presence of necrosis in the pathology reports of ampullary carcinomas will facilitate risk stratification. Keywords: Adenocarcinoma, Ampulla of Vater, Carcinoma, Necrosis, Prognosis
dc.identifier.citationAkar K. E., Bagci P., "Prognostic significance of necrosis in ampullary carcinomas.", Irish journal of medical science, 2024
dc.identifier.doi10.1007/s11845-024-03740-3
dc.identifier.issn0021-1265
dc.identifier.urihttps://avesis.marmara.edu.tr/api/publication/c245bc6b-69f2-4016-b272-8b32bf4ae84f/file
dc.identifier.urihttps://hdl.handle.net/11424/297529
dc.language.isoeng
dc.relation.ispartofIrish journal of medical science
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSağlık Bilimleri
dc.subjectHealth Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectClinical Medicine (MED)
dc.subjectAdenocarcinoma
dc.subjectAmpulla of Vater
dc.subjectCarcinoma
dc.subjectNecrosis
dc.subjectPrognosis
dc.titlePrognostic significance of necrosis in ampullary carcinomas.
dc.typearticle
dspace.entity.typePublication

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