Publication: Determination of finasteride in the tablet form by liquid chromatography and its analytical method validation
| dc.contributor.author | CÜCÜ, AYŞEN | |
| dc.contributor.authors | Demir, H; Cucu, A; Sakarya, S | |
| dc.date.accessioned | 2022-03-12T17:19:20Z | |
| dc.date.accessioned | 2026-01-11T14:03:54Z | |
| dc.date.available | 2022-03-12T17:19:20Z | |
| dc.date.issued | 2006 | |
| dc.description.abstract | A quantitative method for finasteride by liquid chromatography (LC) with UV detector, was validated for its new tablet form Dilaprost (R). Analysis was performed using Nova Pak C-18 column at 60 degrees C. Detection was carried out at a wavelength of 210 nm. The best separation for finasteride peak was achieved by isocratic elution with the mobile phase water/acetonitrile/tetrahydrofuran (80/10/10, v/v/v) and flow rate of 2 mL min(-1). The sample volume injected into liquid chromatography system was 15 mu L. Analytical method validation tests were performed. (c) 2005 Elsevier B.V. All rights reserved. | |
| dc.identifier.doi | 10.1016/j.aca.2005.10.033 | |
| dc.identifier.issn | 0003-2670 | |
| dc.identifier.uri | https://hdl.handle.net/11424/228091 | |
| dc.identifier.wos | WOS:000234963900038 | |
| dc.language.iso | eng | |
| dc.publisher | ELSEVIER SCIENCE BV | |
| dc.relation.ispartof | ANALYTICA CHIMICA ACTA | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | finasteride | |
| dc.subject | Dilaprost (R) | |
| dc.subject | validation | |
| dc.subject | RAT | |
| dc.subject | 5-ALPHA-REDUCTASE | |
| dc.title | Determination of finasteride in the tablet form by liquid chromatography and its analytical method validation | |
| dc.type | article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 255 | |
| oaire.citation.issue | 1-2 | |
| oaire.citation.startPage | 252 | |
| oaire.citation.title | ANALYTICA CHIMICA ACTA | |
| oaire.citation.volume | 557 |