Publication:
Characterization of ciprofloxacin liposomes: derivative ultraviolet spectrophotometric determinations

dc.contributor.authorsGursoy, A; Senyucel, B
dc.date.accessioned2022-03-12T16:56:10Z
dc.date.accessioned2026-01-10T21:24:29Z
dc.date.available2022-03-12T16:56:10Z
dc.date.issued1997
dc.description.abstractNeutral, (-) and (+) charged CF encapsulated liposome formulations prepared with EPC:Chol and DPPC:Chol lipids were investigated for their loading capacity, encapsulation % and release properties. CF amounts in the liposomes were estimated using derivative UV spectroscopy. Among the liposome formulations DPPC:Chol and EPC:Chol neutral formulations had a significantly higher loading capacity and slowest release rate compared with (-) and (+) charged liposomes. The derivative UV spectroscopy was found to be an easy and sensitive method for direct estimation of CF in liposomes.
dc.identifier.doi10.3109/02652049709006827
dc.identifier.issn0265-2048
dc.identifier.pubmed9394258
dc.identifier.urihttps://hdl.handle.net/11424/226686
dc.identifier.wosWOS:A1997YD78000008
dc.language.isoeng
dc.publisherTAYLOR & FRANCIS LTD
dc.relation.ispartofJOURNAL OF MICROENCAPSULATION
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectciprofloxacin
dc.subjectliposome entrapment
dc.subjectdrug release
dc.subjectderivative spectrophotometry
dc.titleCharacterization of ciprofloxacin liposomes: derivative ultraviolet spectrophotometric determinations
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage776
oaire.citation.issue6
oaire.citation.startPage769
oaire.citation.titleJOURNAL OF MICROENCAPSULATION
oaire.citation.volume14

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