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Synthesis, characterization of novel coupling products and 4-arylhydrazono-2-pyrazoline-5-ones as potential antimycobacterial agents

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2002

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Abstract

Novel coupling products 7a-d and 4-arylhydrazono-2-pyrazoline-5-ones 8a-e were synthesized and evaluated for antimycobacterial activity against Mycobacterium tuberculosis H37Rv and Mycobacterium avium. Compound 7b was found to be the most potent derivatives of the 7a-d series by an MIC value of 6.25 microg/ml.

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Microbial Sensitivity Tests, Antitubercular Agents, Pyrazoles, Magnetic Resonance Spectroscopy, Mycobacterium tuberculosis, Mycobacterium avium

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https://hdl.handle.net/11424/249859

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