Publication:
Effects of polyamines and polyamine biosynthetic inhibitors on mitotic activity of Allium cepa root tips

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dc.contributor.authorsUnal, Meral; Palavan-Unsal, Narcin; Tufekci, M. A.
dc.date.accessioned2022-03-12T17:35:12Z
dc.date.accessioned2026-01-10T20:23:46Z
dc.date.available2022-03-12T17:35:12Z
dc.date.issued2008
dc.description.abstractThe genotoxic and cytotoxic effects of exogenous polyamines (PAs), putrescine ( Put), spermidine (Spd), spermine (Spm) and PA biosynthetic inhibitors, alpha-difluoromethylornithine ( DFMO), cyclohexilamine (CHA), methylglioxal bis-(guanylhydrazone) ( MGBG) were investigated in the root meristems of Allium cepa L. The reduction of mitotic index and the induction of chromosomal aberrations such as bridges, stickiness, c-mitotic anaphases, micronuclei, endoredupliction by PAs and PA biosynthetic inhibitors were observed and these were used as evidence of genotoxicity and cytotoxicity.
dc.identifier.doi10.1556/ABiol.59.2008.1.8
dc.identifier.eissn1588-256X
dc.identifier.issn0236-5383
dc.identifier.pubmed18401948
dc.identifier.urihttps://hdl.handle.net/11424/229131
dc.identifier.wosWOS:000253256600008
dc.language.isoeng
dc.publisherAKADEMIAI KIADO ZRT
dc.relation.ispartofACTA BIOLOGICA HUNGARICA
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAllium cepa
dc.subjectchromosome aberration
dc.subjectmitotic activity
dc.subjectpolyamine
dc.subjectpolyamine biosynthetic inhibitor
dc.subjectCELL-CYCLE
dc.subjectSPERMIDINE
dc.subjectGROWTH
dc.titleEffects of polyamines and polyamine biosynthetic inhibitors on mitotic activity of Allium cepa root tips
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage102
oaire.citation.issue1
oaire.citation.startPage93
oaire.citation.titleACTA BIOLOGICA HUNGARICA
oaire.citation.volume59

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