The roles of vitamin b12, 25(oh) d, and folate in primary nocturnal enuresis: A single center experience in an immigration area

Abstract

Introduction & Objectives: In this study, we examined the associations between late preterm (LPT) birth children with nocturnal enuresis and their levels of vitamin B12, folate, iron, and 25(OH)D. Materials & Methods: Between April 2019 and December 2019, 206 children (74 girls, 132 boys) with PNE who presented at the public hospital urology clinics were included as the study group, and 111 healthy children (52 girls, 59 boys) who presented at the same hospital pediatric clinics were included as the control group. We defined primary monosymptomatic nocturnal enuresis as nighttime bedwetting (≥2 nights per week) in children between 5 and 13 years of age. Hospital records of both groups were compared for information such as age, height, weight, vitamin B12, folate, ferritin, iron values, and racial characteristics. Variables were compared using descriptive statistics and the chi-squared and Mann-Whitney U tests.