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Chronic Thromboembolic Pulmonary Hypertension Secondary to Thrombophilia and Incidentally Diagnosed Atrial Septal Defect

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dc.contributor.authorsKilinc, Mehmet; Yaylali, Yalin Tolga; Yildizeli, Bedrettin; Tas, Serpil
dc.date.accessioned2022-03-14T04:31:41Z
dc.date.accessioned2026-01-11T15:35:40Z
dc.date.available2022-03-14T04:31:41Z
dc.date.issued2020
dc.description.abstractA 46-year-old man developed chronic thromboembolic pulmonary hypertension and atrial fibrillation after acute pulmonary embolism. He was found incidentally to have an isolated secundum atrial septal defect, as well as a homozygous mutation for the plasminogen activator inhibitor-1 gene. He was successfully treated with pulmonary endarterectomy and atrial septal defect repair. He has continued to do well on a regimen of dabigatran. (Level of Difficulty: Beginner.).
dc.identifier.doi10.1016/j.jaccas.2020.01.016
dc.identifier.issn2666-0849
dc.identifier.pubmedPMID: 34317315 PMCID: PMC8298561
dc.identifier.urihttps://hdl.handle.net/11424/239077
dc.language.isoeng
dc.relation.ispartofJACC. Case reports
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAF, atrial fibrillation
dc.subjectASD, atrial septal defect
dc.subjectCTEPH, chronic thromboembolic pulmonary hypertension
dc.subjectdabigatran
dc.subjectDOAC, direct oral anticoagulant agent
dc.subjectHF, heart failure
dc.subjectPAI, plasminogen activator inhibitor
dc.subjectPAP, pulmonary arterial pressure
dc.subjectPE, pulmonary embolism
dc.subjectPEA, pulmonary endarterectomy
dc.subjectPH, pulmonary hypertension
dc.subjectplasminogen activator inhibitor-1 (PAI-1) mutation
dc.subjectpulmonary endarterectomy
dc.subjectPVR, pulmonary vascular resistance
dc.subjectRA, right atrial
dc.subjectRHC, right-sided heart catheterization
dc.subjectRV, right ventricular
dc.subjectt-PA, tissue-type plasminogen activator
dc.subjectTAPSE, tricuspid annular excursion
dc.subjectu-PA, urokinase-type plasminogen activator
dc.subjectVTE, venous thromboembolism
dc.titleChronic Thromboembolic Pulmonary Hypertension Secondary to Thrombophilia and Incidentally Diagnosed Atrial Septal Defect
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage661
oaire.citation.startPage658
oaire.citation.titleJACC. Case reports
oaire.citation.volume4

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