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Evaluation of some arylhydrazones of p-aminobenzoic acid hydrazide as antimicrobial agents and their in vitro hepatic microsomal metabolism

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dc.contributor.authorsKomurcu S.G., Rollas S., Ulgen M., Gorrod J.W., Cevikbas A.
dc.date.accessioned2022-03-28T14:50:02Z
dc.date.accessioned2026-01-11T15:23:49Z
dc.date.available2022-03-28T14:50:02Z
dc.date.issued1995
dc.description.abstractBenzoic acid p-amino-[(substitutedphenyl/pyridylmethylene] hydrazide derivatives were synthesised by interaction of p-aminobenzoic acid hydrazide with various aromatic aldehydes. The structures of the compounds were elucidated by use of their UV, IR, 1H-NMR and mass spectral data. These compounds were also evaluated for antimicrobial activity. The in vitro hepatic microsomal metabolism of benzoic acid p-amino-[(4-fluorophenyl)methylene]hydrazide (2d), a selected prototype from these compounds was also carried out.
dc.identifier.issn66648
dc.identifier.pubmed7546542
dc.identifier.urihttps://hdl.handle.net/11424/255286
dc.language.isoeng
dc.relation.ispartofBollettino Chimico Farmaceutico
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectantimicrobial activity
dc.subjecthydrazones
dc.subjectin vitro metabolism
dc.titleEvaluation of some arylhydrazones of p-aminobenzoic acid hydrazide as antimicrobial agents and their in vitro hepatic microsomal metabolism
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage379
oaire.citation.issue7
oaire.citation.startPage375
oaire.citation.titleBollettino Chimico Farmaceutico
oaire.citation.volume134

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