Publication: Can we estimate late-onset sepsis by serial methemoglobin levels? An observational study in preterm neonates
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Abstract
Objective: To assess serial methemoglobin (MetHb) levels in preterm infants as a possible diagnostic method for late-onset sepsis (LOS). Methods: Preterm infants were assigned into two groups: those with culture-proven LOS and controls. Serial MetHb levels were measured. Results: The MetHb values of the LOS group were found to be significantly increased (p 1.75%, optimized for a sensitivity of 81.9% and specificity of 90%. After antimicrobial therapy, MetHb values were found to decrease significantly (p 2% (p 2% is associated with LOS mortality.
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Tıp, Dahili Tıp Bilimleri, Çocuk Sağlığı ve Hastalıkları, Cerrahi Tıp Bilimleri, Patoloji, Yaşam Bilimleri, Sağlık Bilimleri, Temel Tıp Bilimleri, Biyokimya, Temel Bilimler, Medicine, Internal Medicine Sciences, Child Health and Diseases, Surgery Medicine Sciences, Pathology, Life Sciences, Health Sciences, Fundamental Medical Sciences, Biochemistry, Natural Sciences, Klinik Tıp (MED), Yaşam Bilimleri (LIFE), Klinik Tıp, Biyoloji ve Biyokimya, PEDİATRİ, PATOLOJİ, Clinical Medicine (MED), Life Sciences (LIFE), CLINICAL MEDICINE, BIOLOGY & BIOCHEMISTRY, PEDIATRICS, PATHOLOGY, Pediatri, Perinatoloji ve Çocuk Sağlığı, Patoloji ve Adli Tıp, Pediatrics, Perinatology and Child Health, Pathology and Forensic Medicine, Biomarker, late-onset sepsis, methemoglobin, neonate, preterm infants
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Vardar G., Rzayev T., Tezel K. G., ÖZEK E., "Can We Estimate Late-Onset Sepsis by Serial Methemoglobin Levels? An Observational Study in Preterm Neonates", Fetal and Pediatric Pathology, 2023