Publication:
Rituximab for Remission Induction in a Patient with Relapsing Necrotizing Scleritis Associated with Limited Wegener's Granulomatosis

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dc.contributor.authorsOnal, Sumru; Kazokoglu, Haluk; Koc, Aylin; Yavuz, Sule
dc.date.accessioned2022-03-12T16:00:08Z
dc.date.accessioned2026-01-11T05:58:14Z
dc.date.available2022-03-12T16:00:08Z
dc.date.issued2008
dc.description.abstractPurpose: The authors report a case of necrotizing scleritis associated with Wegener's granulomatosis (WG), which was treated with rituximab for relapsing disease. Method: Observational case report. Results: A 32-year-old male patient presented with necrotizing scleritis in his left eye. The patient was diagnosed as having limited WG. Cyclophosphamide was begun. Under maintenance treatment with azathioprine two relapses of scleritis occurred. Since a high cumulative dose of cyclophosphamide (22.5 g) was utilized initially, two intravenous infusions of rituximab 1 g was given. Complete resolution of scleritis occurred. Conclusions: Rituximab may be effective to induce remission in patients with scleritis due to WG.
dc.identifier.doi10.1080/09273940802331643
dc.identifier.issn0927-3948
dc.identifier.pubmed19065418
dc.identifier.urihttps://hdl.handle.net/11424/224599
dc.identifier.wosWOS:000261505500005
dc.language.isoeng
dc.publisherINFORMA HEALTHCARE
dc.relation.ispartofOCULAR IMMUNOLOGY AND INFLAMMATION
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectRituximab
dc.subjectsystemic vasculitis
dc.subjectWegener's granulomatosis
dc.subjectimmunosuppression
dc.subjectnecrotizing
dc.subjectscleritis
dc.subjectTHERAPIES
dc.titleRituximab for Remission Induction in a Patient with Relapsing Necrotizing Scleritis Associated with Limited Wegener's Granulomatosis
dc.typeconferenceObject
dspace.entity.typePublication
oaire.citation.endPage232
oaire.citation.issue5-6
oaire.citation.startPage230
oaire.citation.titleOCULAR IMMUNOLOGY AND INFLAMMATION
oaire.citation.volume16

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