Publication: Balıklarda ağır metal ve pestisitler tarafından indüklenen oksidatif stres mekanizmaları
Abstract
Sucul organizmalar endüstriyel ve tarımsal başta olmak üzere birçok antropojenik aktivite nedeniyle önemli miktarlarda ağır metal ve pestisitlere maruz kalırlar. Ağır metal ve pestisitlerin balıklarda birikmesi oksidatif strese nedeni olan reaktif oksijen türlerinin (ROT) artmasına sebep olur. Bu tip çevresel kirleticiler, reaktif oksijen türlerin hücrelerde direkt olarak artmasına neden olur ve antioksidan kapasiteyi azaltırlar. Bu derleme çalışmasının amacı ağır metal ve pestisitlere maruz kalan balıklarda oksidatif stres belirteçleri ve antioksidan savunma mekanizmalarını irdelemektir
Aquatic organisms are exposed to significant amounts of heavy metals and pesticides due to many anthropogenic activities, particularly industrial and agricultural. Heavy metal and pesticide accumulation may cause an increase in Reactive Oxygen Species (ROS) leading to oxidative stress in fish. These environmental toxicants can promote oxidative damage by directly increasing the cellular concentration of ROS and by reducing the cellular antioxidant capacity. This paper reviews the studies on effects of heavy metals and pesticides exposure on the oxidative stress biomarkers and antioxidant defenses of fish
Aquatic organisms are exposed to significant amounts of heavy metals and pesticides due to many anthropogenic activities, particularly industrial and agricultural. Heavy metal and pesticide accumulation may cause an increase in Reactive Oxygen Species (ROS) leading to oxidative stress in fish. These environmental toxicants can promote oxidative damage by directly increasing the cellular concentration of ROS and by reducing the cellular antioxidant capacity. This paper reviews the studies on effects of heavy metals and pesticides exposure on the oxidative stress biomarkers and antioxidant defenses of fish