Publication:
Synthesis and antibacterial activity of new hydrazide-hydrazones derived from Benzocaine

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dc.contributor.authorKÜÇÜKGÜZEL, ŞÜKRİYE GÜNİZ
dc.contributor.authorsHan, Muhammed Ihsan; Gurol, Guler; Yildirim, Temel; Kalayci, Sadik; Sahin, Fikrettin; Kucukguzel, S. Guniz
dc.date.accessioned2022-03-14T08:24:01Z
dc.date.accessioned2026-01-11T06:47:53Z
dc.date.available2022-03-14T08:24:01Z
dc.date.issued2017-10-04
dc.description.abstractA novel series of new eleven benzocaine hydrazide derivatives, N-(4-{[2-(nonsubstituted/ substitutedfuryl/ phenyl/ pyridinyl/ thienyl/ pyrrole) methylidene]hydrazinyl] carbonyl} phenyl) benzamides [3a-k] have been synthesized in this study. The structures of the new compounds were determined by spectral (FT-IR and H-1-NMR) methods and their purity was proven by elemental analysis and thin layer chromatography. These compounds were evaluated for in vitro antibacterial activity by using micro-well dilution method against Escherichia coli ATCC 10536, Escherichia coli ATCC 15442, Staphylococcus aureus ATCC 6538, Pseudomonas aeruginosa ATCC 15442, Acinetobacter baumannii, Klebsiella pneumonia ATCC 13883.
dc.identifier.doi10.12991/mpj.2017.34
dc.identifier.issn1309-0801
dc.identifier.urihttps://hdl.handle.net/11424/241707
dc.identifier.wosWOS:000417369600027
dc.language.isoeng
dc.publisherMARMARA UNIV, FAC PHARMACY
dc.relation.ispartofMARMARA PHARMACEUTICAL JOURNAL
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntibacterial activity
dc.subjectBenzocaine
dc.subjecthydrazide-hydrazone
dc.subjectazomethine
dc.subjectBIOLOGICAL-ACTIVITIES
dc.subjectANTICANCER AGENTS
dc.subjectANTI-HCV
dc.subjectDERIVATIVES
dc.subjectAPOPTOSIS
dc.subjectETODOLAC
dc.titleSynthesis and antibacterial activity of new hydrazide-hydrazones derived from Benzocaine
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage966
oaire.citation.issue4
oaire.citation.startPage961
oaire.citation.titleMARMARA PHARMACEUTICAL JOURNAL
oaire.citation.volume21

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