Publication:
Determination of Stability Constants of Ibandronate Complexes with Ca(II), Mg(II) and Sr(II)

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dc.contributor.authorsYilmaz, Deniz Cikla; Pekin, Mursit
dc.date.accessioned2022-03-12T22:29:21Z
dc.date.accessioned2026-01-11T13:52:46Z
dc.date.available2022-03-12T22:29:21Z
dc.date.issued2019
dc.description.abstractIn this study, a potentiometric titration method by Calvin-Bjerrum and Irwing-Rosotti was used to investigate binary complexes of ibandronate sodium, a nitrogen-containing bisphosphonate, with Ca(II), Mg(II) and Sr(II). Dissociation constants (pKa) of ibandronate sodium were measured and the stability constants of the complexes formed in aqueous solutions at 22 degrees C (I = 0.11 M NaClO4) were determined. The stoichiometry of ibandronate sodium/metal complexes was found as 1/1 for each metal ion.
dc.identifier.doidoiWOS:000467626500013
dc.identifier.issn2277-3657
dc.identifier.urihttps://hdl.handle.net/11424/235370
dc.identifier.wosWOS:000467626500013
dc.language.isoeng
dc.publisherINT JOURNAL PHARMACEUTICAL RESEARCH & ALLIED SCIENCES
dc.relation.ispartofINTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND ALLIED SCIENCES
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectIbandronate Metal Complexes
dc.subjectBisphosphonates
dc.subjectpKa of Ibandronate
dc.subjectPotentiometric Titration
dc.subjectMETAL-COMPLEXES
dc.subjectBISPHOSPHONATES
dc.subjectACID
dc.subjectALENDRONATE
dc.titleDetermination of Stability Constants of Ibandronate Complexes with Ca(II), Mg(II) and Sr(II)
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage117
oaire.citation.issue2
oaire.citation.startPage111
oaire.citation.titleINTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND ALLIED SCIENCES
oaire.citation.volume8

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