Long-term safety and efficacy of right ventricular outflow tract pacing in patients with permanent pacemakers

Abstract

Objective: The aim of the present study was to investigate long-term safety and change in pacing parameters of right ventricular outflow tract (RVOT) pacing. Methods: This prospectively designed controlled clinical study comprised patients in Group 1 (n= 16) and Group 2 (n= 16) who were paced in RVOT and right ventricular apex (RVA), respectively, and were selected from patients with permanent pacemakers who were routinely followed up at our pacemaker clinic. Commercially available active fixation leads were used in all patients. Pacing parameters were compared at implant and long-term follow-up visits. Statistical analyses were performed using Pearson Chi-Square, nonparametric Mann-Whitney U and Wilcoxon Signed Ranks tests. Results: The mean duration of follow-up was 38.3 +/- 18.0 months for RVOT and 30.4 +/- 20.0 months for RVA (p=0.255). Impedance values, pacing thresholds and R wave amplitudes measured at implant and last pacemaker check did not significantly differ between RVOT and RVA pacing groups. There was no lead dislodgment or any other procedure related complication during follow-up. Conclusion: Right ventricular outflow tract pacing site is safe and pacing impedance and threshold values are comparable with conventional RVA pacing in the long-term. (Anadolu Kardiyol Derg 2008; 8: 350-3)