Diffuse Large B-Cell Lymphoma: A case report

Abstract

Lymphoma is the most common form of blood cancer. Hodgkin lymphoma and non-Hodgkin lymphoma (NHL) are the two major forms of lymphoma. B lymphocytes (B cells) and T lymphocytes (T cells) are the two types of lymphocytes that can develop into lymphomas. B-cell lymphomas are more common than T-cell lymphomas and account for approximately 85% of all NHLs. The most frequent type of NHL is diffuse large B-cell lymphoma (DLBCL). An aggressive type of lymphoma, DLBCL can appear in lymph nodes or outside of the lymphatic system, skin, testes, in the gastrointestinal tract, thyroid gland, breast, bone, or brain. Usually, the first symptom of DLBCL is a painless swelling in the neck, underarms, or groin caused by swollen lymph nodes. Moreover, swelling may be painful for some patients. A 70-year-old male patient who has been reffered to the Marmara University, Faculty of Dentistry, Oral Diagnosis and Radiology Clinic had a complaint of a non-healing and constantly enlarging lesion on the anterior maxillar buccal/palatinal mucosa and the alveolar ridge. Therefore, an incisional biopsy was performed under local anesthesia, and as definite diagnosis, a histopathological examination revealed DLBCL. Consequently, the patient was referred to the Department of Hematology where the lesion was treated. The purpose of this study is to present the case of a male patient with DLBCL and give a literature review.