Publication:
A possible role of Bacteroides fragilis enterotoxin in the aetiology of colorectal cancer

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dc.contributor.authorKARAHASAN, AYŞEGÜL
dc.contributor.authorGÜLLÜOĞLU, MAHMUT BAHADIR
dc.contributor.authorÜLGER, NURVER
dc.contributor.authorsToprak, N. Ulger; Yagci, A.; Gulluoglu, B. M.; Akin, M. L.; Demirkalem, P.; Celenk, T.; Soyletir, G.
dc.date.accessioned2022-03-14T08:24:31Z
dc.date.accessioned2026-01-10T18:32:55Z
dc.date.available2022-03-14T08:24:31Z
dc.date.issued2006-08
dc.description.abstractThe prevalence of enterotoxigenic Bacteroides fragilis (ETBF) was investigated in stool specimens from 73 patients with colorectal cancer and from 59 control patients. Stool specimens were cultured on Bacteroides Bile Esculin agar and B. fragilis was identified by conventional methods. After DNA extraction, the enterotoxin gene (bft) was detected by PCR in 38% of the isolates from colorectal cancer patients, compared with 12% of the isolates from the control group (p 0.009). This is the first study demonstrating an increased prevalence of ETBF in colorectal cancer patients.
dc.identifier.doi10.1111/j.1469-0691.2006.01494.x
dc.identifier.eissn1469-0691
dc.identifier.issn1198-743X
dc.identifier.pubmed16842574
dc.identifier.urihttps://hdl.handle.net/11424/241725
dc.identifier.wosWOS:000238654600011
dc.language.isoeng
dc.publisherELSEVIER SCI LTD
dc.relation.ispartofCLINICAL MICROBIOLOGY AND INFECTION
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBacteroides fragilis
dc.subjectbft gene
dc.subjectcolorectal cancer
dc.subjectenterotoxin
dc.subjectfragilysin
dc.subjectPCR
dc.subjectINTESTINAL EPITHELIAL-CELLS
dc.subjectINFLAMMATORY-BOWEL-DISEASE
dc.subjectEXPRESSION
dc.subjectCHILDREN
dc.subjectMETALLOPROTEASE
dc.subjectSECRETION
dc.subjectDIARRHEA
dc.subjectPROTEIN
dc.subjectTOXIN
dc.subjectIL-8
dc.titleA possible role of Bacteroides fragilis enterotoxin in the aetiology of colorectal cancer
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage786
oaire.citation.issue8
oaire.citation.startPage782
oaire.citation.titleCLINICAL MICROBIOLOGY AND INFECTION
oaire.citation.volume12

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