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D-ALPHA-TOCOPHEROL INHIBITS LOW-DENSITY-LIPOPROTEIN INDUCED PROLIFERATION AND PROTEIN-KINASE-C ACTIVITY IN VASCULAR SMOOTH-MUSCLE CELLS

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dc.contributor.authorsOZER, NK; PALOZZA, P; BOSCOBOINIK, D; AZZI, A
dc.date.accessioned2022-03-14T10:59:06Z
dc.date.accessioned2026-01-10T17:03:50Z
dc.date.available2022-03-14T10:59:06Z
dc.date.issued1993-05-17
dc.description.abstractNative and malondialdehyde modified low density lipoproteins have been shown to stimulate smooth muscle cell proliferation (A7r5) in vitro. The stimulation is associated with an increase of protein kinase C activity. d-alpha-Tocopherol, at physiological concentrations, has been found to inhibit both protein kinase C activity and cell proliferation.
dc.identifier.doi10.1016/0014-5793(93)81592-N
dc.identifier.issn0014-5793
dc.identifier.pubmed8486164
dc.identifier.urihttps://hdl.handle.net/11424/245649
dc.identifier.wosWOS:A1993LB59700023
dc.language.isoeng
dc.publisherELSEVIER SCIENCE BV
dc.relation.ispartofFEBS LETTERS
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectSMOOTH MUSCLE CELL PROLIFERATION
dc.subjectD-ALPHA-TOCOPHEROL
dc.subjectARTERIOSCLEROSIS
dc.subjectLOW DENSITY LIPOPROTEIN
dc.subjectVITAMIN-E
dc.titleD-ALPHA-TOCOPHEROL INHIBITS LOW-DENSITY-LIPOPROTEIN INDUCED PROLIFERATION AND PROTEIN-KINASE-C ACTIVITY IN VASCULAR SMOOTH-MUSCLE CELLS
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage310
oaire.citation.issue3
oaire.citation.startPage307
oaire.citation.titleFEBS LETTERS
oaire.citation.volume322

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