Publication:
THE RECOGNITION OF A DIARYLIMINE AS A METABONATE PRODUCED DURING INCUBATION OF N-BENZYL-4-CHLOROANILINE WITH HEPATIC-MICROSOMAL PREPARATIONS

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dc.contributor.authorsLOW, CM; ULGEN, M; GORROD, JW
dc.date.accessioned2022-03-12T16:57:07Z
dc.date.accessioned2026-01-11T08:29:18Z
dc.date.available2022-03-12T16:57:07Z
dc.date.issued1994
dc.description.abstractEvidence is presented for the formation of N-benzylidene-4-chloroaniline as a metabonate during the metabolism of N-benzyl-4-chloroaniline. Control studies suggest that the diarylimine is formed as a chemical artifact from the debenzylation products (benzaldehyde and 4-chloroaniline). This novel observation indicates a possible pathway to amide formation from N-benzylanilines via diarylimines as intermediates.
dc.identifier.doidoiWOS:A1994NW73400012
dc.identifier.issn0022-3573
dc.identifier.pubmed7996388
dc.identifier.urihttps://hdl.handle.net/11424/226884
dc.identifier.wosWOS:A1994NW73400012
dc.language.isoeng
dc.publisherROYAL PHARMACEUTICAL SOC GREAT BRITAIN
dc.relation.ispartofJOURNAL OF PHARMACY AND PHARMACOLOGY
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectN-OXIDATION
dc.subjectC-OXIDATION
dc.subjectMETABOLISM
dc.titleTHE RECOGNITION OF A DIARYLIMINE AS A METABONATE PRODUCED DURING INCUBATION OF N-BENZYL-4-CHLOROANILINE WITH HEPATIC-MICROSOMAL PREPARATIONS
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage590
oaire.citation.issue7
oaire.citation.startPage585
oaire.citation.titleJOURNAL OF PHARMACY AND PHARMACOLOGY
oaire.citation.volume46

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