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Concordance of immunohistochemistry between core needle biopsy and surgical resection of breast cancer

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dc.contributor.authorsFaruk Erdem KOMBAK;HÜLYA ŞAHİN BALTACI;Hande MOLLAMEMİŞOĞLU;İdris ÖNEM;Handan KAYA;Onur BUĞDAYCI;Erkin ARIBAL
dc.date.accessioned2022-04-04T13:03:07Z
dc.date.accessioned2026-01-10T17:07:55Z
dc.date.available2022-04-04T13:03:07Z
dc.date.issued2017
dc.description.abstract0
dc.description.abstractBackground/aim: The purpose of this study was to evaluate the concordance of immunohistochemical (IHC) parameters of breast lesions between the core needle biopsy (CNB) and the surgical resection specimen. Materials and methods: CNB and resection specimens of female patients were retrospectively analyzed. ER, PR, HER-2, and Ki-67 parameters were compared for each patient. A total of 284 cases were assessed. Forty-one and 48 cases were excluded from the HER-2 and Ki-67 examinations, respectively, because the CNBs did not allow for IHC. Results: Concordance rates were 93.3% for ER, 89.4% for PR, 90.1% for HER-2, and 80.9% for Ki-67. Conclusion: CNB is accurate for the evaluation of the surrogate molecular profile of invasive breast cancer despite the heterogeneity of tumors.
dc.identifier.issn1300-0144;1303-6165
dc.identifier.urihttps://hdl.handle.net/11424/258717
dc.language.isoeng
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCerrahi
dc.titleConcordance of immunohistochemistry between core needle biopsy and surgical resection of breast cancer
dc.typearticle
dspace.entity.typePublication
oaire.citation.endPage1796
oaire.citation.issue6
oaire.citation.startPage1791
oaire.citation.titleTurkish Journal of Medical Sciences
oaire.citation.volume47

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