Publication:
A pilot study for determination of anxiety related SLC6A4 promoter S and L alleles in healthy Turkish athletes

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2017

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C M B ASSOC

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Abstract

We aimed to analyze the allelic distribution of solute carrier family-6 member-4 promoter region in Turkish athletes. Recent studies showed the association of lesser expressing S allele with anxiety. Genotype percentages for LL, LS and SS genotypes were found as 46, 35 and 19, respectively. 38% of the males had LL, %38 had LS and 24% had SS genotypes. Percentages of LL, LS and SS genotypes were 54, 31 and 15 in females, respectively. 15 (58%) male and 18 (69%) females had L, 11 (42%) male and 8 (31%) females had S alleles. Variations in the association of the SLC6A4 alleles with neuropsychiatric disorders according to different nationalities have been reported. This is the first report showing that LL genotype and L allele in Turkish athletes was more frequent than SS genotype and S allele.

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Anxiety, Polymorphism, Serotonin transporter, Sports, Sport psychology, SEROTONIN TRANSPORTER GENE, EXTRACELLULAR 5-HT, 5-HIAA LEVELS, EXERCISE, POLYMORPHISMS, ASSOCIATION, IMPULSIVITY, PERFORMANCE, AGGRESSION, METABOLISM

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https://hdl.handle.net/11424/234586

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