Person: İÇEN, HAYRUNİSA
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İÇEN
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HAYRUNİSA
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Publication Open Access Using microbial responses viewer and a regression approach to assess the eEffect of pH, activity of water and temperature on the survival of campylobacter spp(2022-03-01) OMURTAG KORKMAZ, BURCU İREM; İÇEN, HAYRUNİSA; İÇEN H., Corbo M. R., Sinigaglia M., OMURTAG KORKMAZ B. İ., Bevilacqua A.This study aimed at developing a model for evaluating the survival of various Campylobacter jejuni strains under different conditions in culture media and poultry data from ComBase. Campylobacter data of culture media (116) and poultry (19) were collected from Microbial Responses Viewer, an additional tool of ComBase. The Weibull equation was selected as a suitable model for the analysis of survival data because of the nonlinearity of survival curves. Then, the fitting parameters (first reduction time and shape parameter) were analysed through a Kruskall-Wallis test and box-whisker plots, thus pointing out the existence of two classes of temperature (0-12 degrees C and 15-25 degrees C) and pH (4-6.5 and 7-7.5) acting on the viability of C. jejuni. Finally, a general regression model was used to build a comprehensive function; all factors were significant, but temperature was the most significant variable, followed by pH and water activity. In addition, desirability and prediction profiles highlighted a negative correlation of the first reduction time with temperature and a positive correlation with pH and water activity.Publication Open Access Microbiology and antimicrobial effects of kombucha, a short overview(2023-12-01) İÇEN, HAYRUNİSA; OMURTAG KORKMAZ, BURCU İREM; İÇEN H., Corbo M. R., Sinigaglia M., OMURTAG KORKMAZ B. İ., Bevilacqua A.Kombucha is a beverage usually prepared with black or green tea containing sucrose, and a synbiotic culture of bacteria and yeasts (SCOBY). This paper aims at offering an overview on kombucha microbiota, as well as on its nutritional composition, and antimicrobial effects. The microbiota of kombucha includes acetic acid bacteria (Acetobacter, Gluconobacter, Gluconacetobacter, Komagataeibacter), lactic acid bacteria (Lactobacillus, Lactiplantibacillus, Lacticaseibacillus) and yeasts (Brettanomyces, Candida, Saccharomyces, Zygosaccharomyces), depending on raw materials, starter cultures, and fermentation temperature. The second topic of this review is the production path and kombucha composition, with a synopsis from a quali-quantitative point of view of the most important compounds. Finally, the review examines the antimicrobial potential, focusing on both Gram-positive and Gram-negative bacteria. An open question is on the probiotic status of kombucha; this review offers a contribution to this debate, suggesting for this beverage the status of post-biotic.Publication Metadata only Probiotic Foods From Past To Present In Anatolian Culture(2016-09-07) İÇEN, HAYRUNİSA; KARĞIN, DİCLE; AKDUMAN, GÜL; İçen H., Karğın D., Akduman G., Güneş F. E.Publication Open Access The Relationship Between University Students' Nutritional Status, Cardio-Metabolic Biomarkers and Physical Activity Levels(MARMARA UNIV, INST HEALTH SCIENCES, 2021-03-09) GÜNEŞ, FATMA ESRA; Icen, Hayrunisa; Gunes, Fatma EsraObjective: This study aimed to evaluate the relationship between nutritional status, cardiometabolic biomarkers and physical activity levels in university students. Methods: Firstly, fasting plasma total cholesterol, triglyceride, high-density lipoprotein cholesterol (HDL-C) levels were analyzed from participants' blood samples, and the homeostatic model assessment of insulin resistance (HOMA-IR) values were calculated after measuring fasting plasma glucose and insulin. Participants' weight, height, percentage of body fat, waist and hip circumference were measured and body mass index (BMI) was calculated. The International Physical Activity Questionnaire (IPAQ)and a questionnaire on socio-demographic characteristics were applied to participants. Energy and nutrient intakes were calculated from participants'24-hour dietary recall records. The statistical analysis of data was performed with SPSS version 21 software. For statistical significance, the total type-1 error level was determined as 5%. Results: Most of the participants' energy, dietary fibre, vitamins D and B1, folate, calcium and iron intakes were below recommended levels. HDL-C level was shown to be negatively correlated with total fat and saturated fatty acid intake (p<0.05). Omega-3 intakes of participants were negatively correlated with fasting plasma insulin and HOMA-IR (p<0.05).HDL-C was negatively correlated with BMI and waist-to-hip ratio, while fasting plasma insulin, triglyceride levels and HOMA-IR values were positively correlated with them (p<0.05). According to the IPAQ, it was found that 15.9% of participants had a low level of physical activity and 66.1% of them had a moderate level of physical activity. Conclusion: It is concluded that providing nutrition education and counselling services to students, improving campus facilities for physical activity are necessary for cardiometabolic health.Publication Open Access Akdeniz Diyetinin Kognitif Fonksiyonlar Üzerine Etkileri(2019) GÜNEŞ, FATMA ESRA; Hayrunisa İÇEN;Simay FERELİ;İZEL AYCAN BAŞOĞLU;Fatma Esra GÜNEŞDünya nüfusunun gittikçe yaşlanmasına bağlı olarak demans ve Alzheimer hastalığı gibi kognitif fonksiyonların azalmasıyla ilişkili hastalıkların sıklığı yükselmekte ve bu hastalıklara sahip kişilerin bakımı, ekonomik ve sosyal yükü artırmaktadır. Günümüzde bu hastalıkların oluşmasınıgeciktirmek veya prognozunu yavaşlatmak için preklinik aşamalarda alınacak tedbirler önem kazanmaktadır. Bu hastalıkların etiyolojisi tam olarak bilinmemekle beraber kabul gören, kesinleşmişrisk faktörleri; yaş, kadın cinsiyet ve aile öyküsüdür. Kognitif fonksiyonlarda azalma çeşitli vasküler risk faktörleriyle ilişkilidir, buradan yola çıkılarak beslenmenin rolünü araştırmaya yönelik birçok çalışma yapılmıştır. Özellikle hastalığın önlenmesinde ya da başlamasının ertelenmesinde diyetönemli bir faktördür. Bu çalışmada, Akdeniz diyetine uyumun kognitif fonksiyonlardaki gerilemeyi geciktirmeye ya da önlemeye yönelik etkilerinin araştırılması amaçlanmıştır. Akdeniz diyetinin kognitif fonksiyonlardaki azalmaya bağlı hastalıklarda ve bunlardan kaynaklanan ölümlerdeazalma sağladığı görülmüştür. Akdeniz diyeti özel bir diyet modeli olmayıp, Akdeniz’e kıyısı olanülkelerin geleneksel beslenme biçimidir. Bu beslenme biçimi yüksek meyve-sebze, tahıl ve kurubaklagil ile düşük doymuş yağ, kırmızı et ve et ürünleri, orta düzeyde balık ve alkol (özellikle şarap),düşük-orta düzeyde süt ürünleri tüketimi ile karakterize, çoklu besin ögesi alımı sağlayan en sağlıklı beslenme modellerindendir. Akdeniz diyeti bileşenlerinin sağlığı koruyucu etkisine dair tutarlıkanıtlar mevcuttur ve bu durum besin ögelerinin interaktif ve sinerjik kombinasyonlarından kaynaklanmaktadır. Bu açıdan sağlık üzerine etkisinin değerlendirilmesi için tek bir besin ögesinin etkisi yerine, besinlerin bir arada tüketildiğindeki etkileri değerlendirilmelidir. Son yıllarda birçokaraştırmada, Akdeniz diyetine uyumun kognitif fonksiyonlarda gerilemeyi azalttığı gösterilse denet sonuçların ortaya konulması gerekmektedir.