Person: İNANIR, SABAHAT
Loading...
Email Address
Birth Date
Research Projects
Organizational Units
Job Title
Last Name
İNANIR
First Name
SABAHAT
Name
26 results
Search Results
Now showing 1 - 10 of 26
Publication Open Access Langerhans Hucreli Histiyositoz Tanili Hastada Soliter Kemik Lezyonunun Takibinde Kemik Sintigrafi ve SPECT/BT'nin Rolu(GALENOS YAYINCILIK, 2021-10-01) TUROĞLU, HALİL TURGUT; Kesim, Selin; Turoglu, Halil Turgut; Inanir, Sabahat; Ozguven, Salih; Erdil, Tanju YusufLangerhans' cell histiocytosis (LCH) is a rare disease observed in childhood characterized by the proliferation of Langerhans' cells resulting in focal or systemic manifestations (including the bones). Here, we present a pediatric case with a localized biopsy-proven LCH, who underwent progression from solitary to multifocal form detected on bone scintigraphy and single photon emission computerized tomography/computed tomography (SPECT/CT) performed within four months. Emphasizing on localized bone pain (predictive of osseous LCH) and local tenderness and swelling usually guides the nuclear physician to perform additional SPECT/CT with presumably an improvement of the diagnostic accuracy as demonstrated in our case.Publication Metadata only Simple provocative maneuvers in renal transplant scintigraphy for detecting urine leak(SPRINGER, 2007) DEDE, FUAT; Dede, Fuat; Ones, Tunc; Caliskan, Billur; Civen, Huseyin; Erdil, Tanju Y.; Inanir, Sabahat; Tuglular, Zubeyde S.; Yegen, Cumhur; Akoglu, Emel; Turoglu, Halil T.Urine leak in the early postoperative period following renal transplantation is a serious complication requiring early identification and aggressive intervention, which significantly reduces the morbidity and mortality. Renal transplant scintigraphy is a noninvasive method to evaluate the perfusion and function of a transplanted kidney and urinary drainage including urine leak. Here, we reported two cases in which the standard transplant renogram failed to demonstrate urine leak. The cases were referred for a diethylenetriaminepentaacetic acid renogram following the transplantation to evaluate the cause of symptoms or elevated serum creatinine level. In both the cases, urine leak was successfully detected following simple maneuvers such as diuretic administration or Foley catheter irrigation. Renal transplant scintigraphy is an effective and safe technique and the use of these simple maneuvers can enhance the diagnostic sensitivity of the transplant renogram in the detection of urine leak.Publication Open Access Flip-flop phenomenon in systemic sclerosis on fluorodeoxyglucose positron emission tomography/computed tomography(WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2015) DİRESKENELİ, RAFİ HANER; Oksuzoglu, Kevser; Ozen, Gulsen; Inanir, Sabahat; Direskeneli, Rafi HanerSystemic sclerosis (SSc) is a rare autoimmune disease, which may affect multiple organ systems. Fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) can demonstrate the degree and anatomical extent of involvement in the entire body and coexisting malignancies in connective tissue diseases. We present a case of SSc with an increased 18F-FDG uptake in the cutaneous and subcutaneous tissues even higher than the neighboring skeletal muscles (flip-flop phenomenon, that is, an increased 18F-FDG uptake in the skin but a decreased 18F-FDG uptake in the skeletal muscles).Publication Metadata only FDG PET/CT Appearance of Multi-Regional Elastofibroma: Original Image(ORTADOGU AD PRES & PUBL CO, 2012) DEDE, FUAT; Gungor, Serkan; Ones, Tunc; Aras, Mustafa; Dede, Fuat; Inanir, Sabahat; Erdil, T. Yusuf; Turoglu, H. TurgutPublication Metadata only Relative renal function with MAG-3 and DMSA in children with unilateral hydronephrosis(SPRINGER, 2010) İNANIR, SABAHAT; Aktas, Gul Ege; Inanir, SabahatTc-99m DMSA renal cortical scan is a reference method for determining relative renal function (RRF). Tc-99m MAG-3 is also recommended for the estimation of RRF, particularly in young children. The aims of this study were to compare MAG-3 and DMSA RRF estimations and to assess the reproducibility of these estimations in children with unilateral hydronephrosis. We reviewed MAG-3 and DMSA scans of 19 children with unilateral hydronephrosis and a normal contralateral unit. All were imaged with 2 agents within 3 months. MAG-3 RRF was calculated using 2 different time intervals (1-2 and 2-3 min) and perirenal C-type region of background activity. No background correction method was used in the calculation of DMSA RRF. All data were processed twice by two independent operators. In the repeated estimates of MAG-3 RRF, the maximum mean intra-observer and inter-observer differences were 0.9% (SD 1.7%) and 1.4% (SD 3.3%), respectively. Intra-method analysis showed statistically significant agreement between repeated measures of RRF for two agents as well as for two operators (intra-class cross-correlation coefficients of early and later phase of MAG-3 and DMSA RRF values were 0.979, 0.993 and 0.996 for operator 1, and 0.986, 0.973 and 0.995 for operator 2, respectively; p < 0.001). There were statistically significant correlations between the MAG-3 and DMSA RRF estimations (r = 0.763/0.766 at 1-2 min, 0.835/0.825 at 2-3 min for the repeated measures of RRF for operator 1, and 0.812/0.793 and 0.83/0.89 for operator 2, respectively; p < 0.01, Pearson). Each scan classified as normal or abnormal according to RRF values inter-method analysis showed statistically significant agreement between MAG-3 and DMSA RRF estimations (Kappa statistics). However, there was a slight disagreement between the methods especially in infants and cases with higher grade of hydronephrosis, when 5% difference in estimations and supranormal estimates of RRF were taken into consideration. Although DMSA and MAG-3 RRF estimations demonstrated a statistically significant correlation with good reproducibility in children with unilateral hydronephrosis, overall the finding of surprising estimates of kidney function with MAG-3 calls attention to the existence of some problems especially in infants and in those with higher grades of hydronephrotic kidneys.Publication Open Access A rare case mimicking positron emission tomography/computed tomography mismatch: Hepatic subcapsular hematoma(WOLTERS KLUWER MEDKNOW PUBLICATIONS, 2015) TÜNEY, DAVUT; Inanir, Sabahat; Oksuzoglu, Kevser; Aras, Mustafa; Tuney, DavutSubcapsular collections of bile, air or blood in the liver have been described following transhepatic procedures due to the leakage of bile and blood from the percutaneous puncture at the surface of the liver. Herein we presented the subcapsular collection led to a mismatch between functional and anatomical boundaries of the liver.Publication Metadata only An unusual disease mimicking congenital nephrotic syndrome: Answers(SPRINGER, 2021) ALPAY, HARİKA; Yildiz, Nurdan; Sak, Mehtap; Inanir, Sabahat; Akkelle, Bilge Sahin; Alpay, HarikaPublication Metadata only Ektopik Paratiroid Bezlerini Saptamada Dual Faz MIBI Sintigrafisi ve SPECT/BT Görüntülemesinin Rolü Tek Merkezli Çalışma(2023-04-26) KESİM, SELİN; TUROĞLU, HALİL TURGUT; FİLİZOĞLU, NUH; ÖZGÜVEN, SALİH; İNANIR, SABAHAT; DEDE, FUAT; ÖNEŞ, TUNÇ; ERDİL, TANJU YUSUF; BALABAN GENÇ, ZEYNEP CEREN; Kesim S., Turoğlu H. T., Balaban Genç Z. C., Filizoğlu N., Niftaliyeva K., Kıssa T. N., Öksüzoğlu K., Özgüven S., Şen F., İnanır S., et al.Amaç: Primer hiperparatiroidisi olan hastalardan, daha önce hiç araştırılmamış hasta popülasyonunda ektopik paratiroid adenomu (EPA) prevalansı yaklaşık %20 iken; tekrar ameliyat edilen popülasyonda EPA prevalansın %66’ya kadar yükselebildiği literatürde bildirilmiştir. Ektopik bezler karotis bifurkasyonundan aortopulmoner pencereye kadar herhangi bir yerde olabilir. Bu çalışmada, hastanemize gelip, primer hiperparatiroidi nedeniyle paratiroid sintigrafisi çekilen hastalarda ektopik paratiroid bezi sıklığı ve tek foton emisyon bilgisayarlı tomografi/bilgisayarlı tomografi (SPECT/BT) tekniğinin katkısı retrospektif olarak araştırıldı.Yöntem: Haziran 2015-Ocak 2023 tarihleri arasında Nükleer Tıp Kliniğine refere edilen 300 primer hiperparatiroidi tanılı olguya preoperatif lokalizasyon amacıyla anterior mediasten dahil, dual faz Tc-99m-MIBI planar sintigrafileriyle SPECT/BT tomografik görüntüleme yapıldı. Renal kalkül veya kemik mineral yoğunluğunda azalma gibi son organ hasarı bulunan, ciddi hiperkalsemisi bulunan, semptomatik hastalar, 50 yaş ve altında tanı alan olgular ile klinik veya biyokimyasal kanıtların paratiroid karsinomu ile uyumlu olduğu olgular paratiroidektomiye yönlendirildi. Hastaların korele eden ameliyat bulguları ve postop patoloji sonuçları retrospektif olarak incelendi. Postop PTH düzeylerinin düşmesi, hiperkalseminin, hasta semptomlarının kaybolması ve renal kalkül gibi klinik bulguların nüks etmemesi, primer paratiroid adenomu lokalizasyonu ve tedavisinin başarılı olması olarak değerlendirildi. Bulgular: MIBI sintigrafisinde 300 hastadan 24 olguda (%8) ektopik yerleşimli paratiroid bezi saptandı bunların 7 tanesi ameliyat ile konfirme edildi. Histopatolojik olarak bu ektopik bezlerden 5 tanesi paratiroit adenomu, 2 tanesi paratiroid hiperplazisi olarak raporlandı. Yirmi dört hastanın 4 tanesi erkek, 20 tanesi kadın olup; hasta yaşları 45 ile 82 arasında değişmekteydi (ortalama yaş; 64,2). Hastaların ortalama kalsiyum değeri 11,3±0,9 mg/dL iken, ortalama parathormon değeri 258±469 ng/L olarak hesaplandı. Adenom boyutları ortalama 10,5±4,8 mm olarak ölçüldü. Ektopik paratiroidlerin yerleşim yerleri en sık görülme yerlerinden başlayarak azalan sıklık sayısına göre, mediastinal, paraözofageal, intratiroidal, submandibular, jugulum düzeyi, trakeoözofageal ve karotis kılıfı idi. Sonuç: Ektopik paratiroit bezlerine, tiroit bezi içerisinde veya angulus mandibuladan aşağı anterior mediastene kadar uzanan, timofarengeal kanal boyunca rastlanabilir. Süperior paratiroid bezleri, embriyolojik olarak 4. Yutak kesesinden kaynaklanır ve posterolateral loblarına yakın yerleşim gösterdikleri tiroit beziyle birlikte aşağı inerler. İnferior paratiroit bezleri ise, embriyolojik olarak 3. yutak kesesinden kaynaklanır ve timusla birlikte kaudale doğru göç ederler. Alt paratiroid bezlerinin yerleşimi tiroit bezinin içinde ve yakınında, karotis bifurkasyonunda, alt boyunda veya mediastende olabilir.Ektopik yerleşime, inferior paratiroit bezlerinde daha sık rastlanmaktadır. Ektopik adenomlar hem Tc-99m-MIBI görüntülemesi ile lokalize etmekte hem de cerrahi rezeksiyonda zorluk çıkarmaktadır. Hibrid SPECT/BT görüntüleme tekniğininin kullanılması, deneyim ve multidisipliner işbirliği ile optimal sonuç elde edilebilir. Anahtar Kelimeler: Primer hiperparatiroidi, ektopik paratiroid adenomu, dual faz MIBI sintigrafisi, SPECT/BTPublication Metadata only Invasive urothelial carcinoma detected in bladder diverticulum with FDG PET/CT: A rare case with negative cystoscopy(ELSEVIER DOYMA SL, 2014) TUROĞLU, HALİL TURGUT; Ozguven, Salih; Maleki, Reza; Ones, Tunc; Inanir, Sabahat; Erdil, Tanju Yusuf; Turoglu, Halil TurgutPublication Open Access Long-Term Results of Fixed High-Dose I-131 Treatment for Toxic Nodular Goiter: Higher Euthyroidism Rates in Geriatric Patients(GALENOS YAYINCILIK, 2015-10-05) DEDE, FUAT; Aktas, Gul Ege; Turoglu, Halil Turgut; Erdil, Tanju Yusuf; Inanir, Sabahat; Dede, FuatObjective: Geriatric patient population has special importance due to particular challenges. In addition to the increase in incidence of toxic nodular goiter (TNG) with age, it has a high incidence in the regions of low-medium iodine intake such as in our country. The aim of this study was to evaluate the overall outcome of high fixed dose radioiodine (RAI) therapy, and investigate the particular differences in the geriatric patient population. Methods: One hundred and three TNG patients treated with high dose I-131 (370-740 MBq) were retrospectively reviewed. The baseline characteristics; age, gender, scintigraphic patterns and thyroid function tests before and after treatment, as well as follow-up, duration of antithyroid drug (ATD) medication and achievement of euthyroid or hypothyroid state were evaluated. The patient population was divided into two groups as those=>65 years and those who were younger, in order to assess the effect of age. Results: Treatment success was 90% with single dose RAI therapy. Hyperthyroidism was treated in 7 +/- 7, 2 months after RAI administration. At the end of the first year, overall hypothyroidism rate was 30% and euthyroid state was achieved in 70% of patients. Age was found to be the only statistically significant variable effecting outcome. A higher ratio of euthyroidism was achieved in the geriatric patient population. Conclusion: High fixed dose I-131 treatment should be preferred in geriatric TNG patients in order to treat persistent hyperthyroidism rapidly. The result of this study suggests that high fixed dose RAI therapy is a successful modality in treatni g TNG, and high rates of euthyroidism can be achieved in geriatric patients.
- «
- 1 (current)
- 2
- 3
- »