Publication:
Langerhans Hucreli Histiyositoz Tanili Hastada Soliter Kemik Lezyonunun Takibinde Kemik Sintigrafi ve SPECT/BT'nin Rolu

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2021-10-01

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GALENOS YAYINCILIK

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Abstract

Langerhans' cell histiocytosis (LCH) is a rare disease observed in childhood characterized by the proliferation of Langerhans' cells resulting in focal or systemic manifestations (including the bones). Here, we present a pediatric case with a localized biopsy-proven LCH, who underwent progression from solitary to multifocal form detected on bone scintigraphy and single photon emission computerized tomography/computed tomography (SPECT/CT) performed within four months. Emphasizing on localized bone pain (predictive of osseous LCH) and local tenderness and swelling usually guides the nuclear physician to perform additional SPECT/CT with presumably an improvement of the diagnostic accuracy as demonstrated in our case.

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Langerhans' cell histiocytosis, technetium-99m-methylene diphosphonate bone scintigraphy, bone SPECT/CT, EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY, CELL HISTIOCYTOSIS, BONE-SCINTIGRAPHY, LESIONS

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