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Synthesis of novel pyrazoline derivatives and evaluation of their antimicrobial activity

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dc.contributor.authorTOK, FATİH
dc.contributor.authorGÜRBÜZ, BURÇAK
dc.contributor.authorKAYMAKÇIOĞLU, BEDİA
dc.contributor.authorsTOK F., Doğan M. O. , GÜRBÜZ B., Koçyiğit-Kaymakçioğlu B.
dc.date.accessioned2022-12-23T08:54:03Z
dc.date.available2022-12-23T08:54:03Z
dc.date.issued2022-01-01
dc.description.abstract© 2022 Marmara University Press.In this study, new nine pyrazoline derivatives were synthesized from chalcone derivatives. The antimicrobial activity of nine pyrazoline derivatives to four standard bacterial strains (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis) and four standard yeast strains (Candida albicans, Candida glabrata, Candida parapsilosis, Candida tropicalis) was investigated by the microdilution method for in accordance with the Clinical and Laboratory Standards Institute (CLSI) standard, and the Minimal Inhibitory Concentration (MIC) values of these derivatives were determined. Among these derivatives; compounds 7 and 8 against bacterial strains and compounds 2 and 3 against yeast strains exhibited good antimicrobial activity.
dc.identifier.citationTOK F., Doğan M. O. , GÜRBÜZ B., Koçyiğit-Kaymakçioğlu B., "Synthesis of novel pyrazoline derivatives and evaluation of their antimicrobial activity", Journal of Research in Pharmacy, cilt.26, sa.5, ss.1453-1460, 2022
dc.identifier.doi10.29228/jrp.238
dc.identifier.endpage1460
dc.identifier.issn2630-6344
dc.identifier.issue5
dc.identifier.startpage1453
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85137881468&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/283906
dc.identifier.volume26
dc.language.isoeng
dc.relation.ispartofJournal of Research in Pharmacy
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTemel Eczacılık Bilimleri
dc.subjectEczacılık
dc.subjectYaşam Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTemel Bilimler
dc.subjectBasic Pharmaceutics Sciences
dc.subjectPharmacology and Therapeutics
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectNatural Sciences
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectLife Sciences (LIFE)
dc.subjectPHARMACOLOGY & TOXICOLOGY
dc.subjectPHARMACOLOGY & PHARMACY
dc.subjectGenel Farmakoloji, Toksikoloji ve Eczacılık
dc.subjectFarmakoloji (tıbbi)
dc.subjectGeneral Pharmacology, Toxicology and Pharmaceutics
dc.subjectPharmacology (medical)
dc.subjectbacteria
dc.subjectMIC
dc.subjectPyrazoline
dc.subjectyeast
dc.subjectPyrazoline
dc.subjectbacteria
dc.subjectyeast
dc.subjectMIC
dc.titleSynthesis of novel pyrazoline derivatives and evaluation of their antimicrobial activity
dc.typearticle
dspace.entity.typePublication
local.avesis.ida211ff4e-8d6e-4adb-8653-972765da3efa
local.indexed.atSCOPUS
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