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Prognostic value of the lactate-albumin difference for predicting in-hospital mortality in critically ill patients with sepsis

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dc.contributor.authorÇORMAN DİNÇER, PELİN
dc.contributor.authorKARARMAZ, ALPER
dc.contributor.authorsTore Altun G., Arslantas M. K., ÇORMAN DİNÇER P., Arslantas R., KARARMAZ A.
dc.date.accessioned2023-02-20T10:22:39Z
dc.date.available2023-02-20T10:22:39Z
dc.date.issued2022-01-01
dc.description.abstractObjective: To evaluate the prognostic performance of the lactate–albumin difference (LAD), maximum lactate levels, and the Sequential Organ Failure Assessment (SOFA) score taken on the first day in critically ill patients with sepsis, on in-hospital mortality and 90-day survival. Patients and Methods: Data from the Medical Information Mart for Intensive Care III (MIMIC III) version 1.4 were evaluated retrospectively. The first day data of adult patients with sepsis diagnosed according to the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) criteria were recorded. The effectiveness of all diagnostic modalities on admission was analyzed to predict in-hospital mortality and 90-day survival. Results: In-hospital mortality was 20.3% among the 2270 patients included in this study. The area below the receiver operating characteristic curve (AUC) value of the LAD was higher than lactate for predicting mortality (AUC, 0.691; 95% confidence interval [CI], 0.663–0.718; p< 0.01, and AUC, 0.675; 95% CI, 0.646–0.703; p< 0.01, respectively), and the AUC of SOFA score was the highest (AUC, 0.716; 95% CI, 0.663–0.718). The optimal cutoff of LAD was 0.7. Conclusion: In addition to its easy and simple calculability relative to the SOFA, the prognostic performance of LAD was superior to maximum lactate levels for predicting in-hospital mortality and 90-day survival in adult patients with sepsis.
dc.identifier.citationTore Altun G., Arslantas M. K., ÇORMAN DİNÇER P., Arslantas R., KARARMAZ A., "Prognostic value of the lactate-albumin difference for predicting in-hospital mortality in critically ill patients with sepsis", MARMARA MEDICAL JOURNAL, cilt.35, sa.1, ss.61-66, 2022
dc.identifier.doi10.5472/marumj.1059093
dc.identifier.endpage66
dc.identifier.issn1309-9469
dc.identifier.issue1
dc.identifier.startpage61
dc.identifier.urihttps://avesis.marmara.edu.tr/api/publication/45ba3ddc-59b1-453a-979c-48aeb68026b0/file
dc.identifier.urihttps://hdl.handle.net/11424/286574
dc.identifier.volume35
dc.language.isoeng
dc.relation.ispartofMARMARA MEDICAL JOURNAL
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectMedicine
dc.subjectHealth Sciences
dc.subjectFundamental Medical Sciences
dc.subjectTIP, GENEL & DAHİLİ
dc.subjectKlinik Tıp
dc.subjectKlinik Tıp (MED)
dc.subjectMEDICINE, GENERAL & INTERNAL
dc.subjectCLINICAL MEDICINE
dc.subjectClinical Medicine (MED)
dc.subjectFamily Practice
dc.subjectFundamentals and Skills
dc.subjectGeneral Health Professions
dc.subjectPathophysiology
dc.subjectInternal Medicine
dc.subjectAssessment and Diagnosis
dc.subjectMedicine (miscellaneous)
dc.subjectGeneral Medicine
dc.subjectLactate-albumin difference
dc.subjectLactate
dc.subjectSepsis
dc.subjectIn-hospital mortality
dc.subjectSurvival
dc.subjectORGAN FAILURE
dc.subjectLactate-albumin difference
dc.subjectLactate
dc.subjectSepsis
dc.subjectIn-hospital mortality
dc.subjectSurviva
dc.titlePrognostic value of the lactate-albumin difference for predicting in-hospital mortality in critically ill patients with sepsis
dc.typearticle
dspace.entity.typePublication
local.avesis.id45ba3ddc-59b1-453a-979c-48aeb68026b0
local.indexed.atWOS
local.indexed.atSCOPUS
relation.isAuthorOfPublication0b90bbca-2634-46be-b094-a80bfb63ac43
relation.isAuthorOfPublication82a34ee2-92e5-4f63-a34a-297f183aa79b
relation.isAuthorOfPublication.latestForDiscovery0b90bbca-2634-46be-b094-a80bfb63ac43

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