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Reappraisal of T1b gallbladder cancer (GBC): clinicopathologic analysis of 473 in situ and invasive GBCs and critical review of the literature highlights its rarity, and that it has a very good prognosis

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dc.contributor.authorBAĞCI ÇULÇİ, PELİN
dc.contributor.authorsPehlivanoglu B., Akkas G., Memis B., Basturk O., Reid M. D., Saka B., Dursun N., Bagci P., Balci S., Sarmiento J., et al.
dc.date.accessioned2024-08-12T07:54:46Z
dc.date.available2024-08-12T07:54:46Z
dc.date.issued2023-02-01
dc.description.abstractThere are highly conflicting data on relative frequency (2–32%), prognosis, and management of pT1b-gallbladder carcinoma (GBC), with 5-year survival ranging from > 90% in East/Chile where cholecystectomy is regarded as curative, versus 90%, similar to findings in the East. This supports the inclusion of pT1b in the \"early GBC\" category, as is typically done in high-incidence regions. Pathologic mis-staging of pT2 as pT1 is not uncommon. Cases should not be classified as pT1b unless extensive, preferably total, sampling of the gallbladder to rule out a subtle pT2 is performed. Critical appraisal of the literature reveals that the Western guidelines are based on either SEER or mis-interpretation of stage IB cases as \"pT1b.\" Although the prognosis of pT1b-GBC is very good, additional surgery (radical cholecystectomy) may be indicated, and long-term surveillance of the biliary tract is warranted.
dc.identifier.citationPehlivanoglu B., Akkas G., Memis B., Basturk O., Reid M. D., Saka B., Dursun N., Bagci P., Balci S., Sarmiento J., et al., "Reappraisal of T1b gallbladder cancer (GBC): clinicopathologic analysis of 473 in situ and invasive GBCs and critical review of the literature highlights its rarity, and that it has a very good prognosis", Virchows Archiv, cilt.482, sa.2, ss.311-323, 2023
dc.identifier.doi10.1007/s00428-022-03482-6
dc.identifier.endpage323
dc.identifier.issn0945-6317
dc.identifier.issue2
dc.identifier.startpage311
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85145162798&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/297530
dc.identifier.volume482
dc.language.isoeng
dc.relation.ispartofVirchows Archiv
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTıp
dc.subjectHistoloji-Embriyoloji
dc.subjectCerrahi Tıp Bilimleri
dc.subjectPatoloji
dc.subjectYaşam Bilimleri
dc.subjectMoleküler Biyoloji ve Genetik
dc.subjectSağlık Bilimleri
dc.subjectTemel Tıp Bilimleri
dc.subjectBiyokimya
dc.subjectTemel Bilimler
dc.subjectMedicine
dc.subjectHistology and Embryology
dc.subjectSurgery Medicine Sciences
dc.subjectPathology
dc.subjectLife Sciences
dc.subjectMolecular Biology and Genetics
dc.subjectHealth Sciences
dc.subjectFundamental Medical Sciences
dc.subjectBiochemistry
dc.subjectNatural Sciences
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectBiyoloji ve Biyokimya
dc.subjectPATOLOJİ
dc.subjectHÜCRE BİYOLOJİSİ
dc.subjectLife Sciences (LIFE)
dc.subjectBIOLOGY & BIOCHEMISTRY
dc.subjectMOLECULAR BIOLOGY & GENETICS
dc.subjectPATHOLOGY
dc.subjectCELL BIOLOGY
dc.subjectPatoloji ve Adli Tıp
dc.subjectMoleküler Biyoloji
dc.subjectHücre Biyolojisi
dc.subjectPathology and Forensic Medicine
dc.subjectMolecular Biology
dc.subjectCell Biology
dc.subjectGallbladder carcinoma
dc.subjectPathologic sampling
dc.subjectpT1b
dc.subjectSurvival
dc.titleReappraisal of T1b gallbladder cancer (GBC): clinicopathologic analysis of 473 in situ and invasive GBCs and critical review of the literature highlights its rarity, and that it has a very good prognosis
dc.typearticle
dspace.entity.typePublication
local.avesis.ideda5e469-f9a5-461d-aa4d-da64aa5553b3
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublication08d32d97-3eab-4e66-9cb5-3177601d83e9
relation.isAuthorOfPublication.latestForDiscovery08d32d97-3eab-4e66-9cb5-3177601d83e9

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