Publication: The Longitudinal Evolution of Post-COVID-19 Outcomes Among Hemodialysis Patients in Turkey
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2022-06-01
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Introduction: Hemodialysis (HD) patients have increased risk for short-term adverse outcomes of COVID-19. However, complications and survival at the post-COVID-19 period have not been published extensively.Methods: We conducted a national, multicenter observational study that included adult maintenance HD patients recovered from confirmed COVID-19. A control HD group without COVID-19 was selected from patients in the same center. We investigated the characteristics and outcomes in the follow-up of HD patients and compare them with the non-COVID-19 group.Results: A total of 1223 patients (635 patients in COVID-19 group, 588 patients in non-COVID-19 group) from 47 centers were included in the study. The patients\" baseline and HD characteristics were almost similar. The 28th-day mortality and mortality between 28th day and 90th day were higher in the COVID-19 group than non-COVID-19 group (19 [3.0%] patients vs. none [0%]; 15 [2.4%] patients vs. 4 [0.7%] patients, respectively). The presence of respiratory symptoms, rehospitalization, need for home oxygen therapy, lower respiratory tract infection, and arteriovenous (AV) fistula thrombosis was significantly higher in the COVID-19 group in both the first 28 days and between 28 and 90 days. In the multivariable analysis, age (odds ratio [OR] [95% CI]: 1.029 [1.004-1.056]), group (COVID-19 group vs. non-COVID-19 group) (OR [95% CI]: 7.258 [2.538-20.751]), and vascular access type (tunneled catheter/AV fistula) (OR [95% CI]: 2.512 [1.249-5.051]) were found as independent parameters related to 90-day mortality.Conclusion: In the post-COVID-19 period, maintenance HD patients who have had COVID-19 have increased rehospitalization, respiratory problems, vascular access problems, and high mortality compared with the non-COVID-19 HD patients.
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Tıp, Sağlık Bilimleri, Dahili Tıp Bilimleri, İç Hastalıkları, Nefroloji, Medicine, Health Sciences, Internal Medicine Sciences, Internal Diseases, Nephrology, ÜROLOJİ VE NEFROLOJİ, Klinik Tıp, Klinik Tıp (MED), UROLOGY & NEPHROLOGY, CLINICAL MEDICINE, Clinical Medicine (MED), Üroloji, Urology, COVID-19, hemodialysis, nationwide study, outcome, MORTALITY-RATES, TRANSPLANT, COVID-19, hemodialysis, nationwide study, outcome
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ÖZTÜRK S., Turgutalp K., ARICI M., Gorgulu N., Tonbul H. Z., EREN N., GENÇER V., Ayli M. D., Pembegul I., Dolarslan M. E., et al., "The Longitudinal Evolution of Post-COVID-19 Outcomes Among Hemodialysis Patients in Turkey", KIDNEY INTERNATIONAL REPORTS, cilt.7, sa.6, ss.1393-1405, 2022