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Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjögren's syndrome: an OMERACT reliability exercise

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dc.contributor.authorİNANÇ, GÜZİDE NEVSUN
dc.contributor.authorsHočevar A., Bruyn G. A. , Terslev L., De Agustin J. J. , MacCarter D., Chrysidis S., Collado P., Dejaco C., Fana V., Filippou G., et al.
dc.date.accessioned2022-12-26T10:41:53Z
dc.date.available2022-12-26T10:41:53Z
dc.date.issued2022-08-03
dc.description.abstract© The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com.OBJECTIVE: The aim of this exercise from the OMERACT Ultrasound subgroup on Sjögren\"s syndrome was to develop and assess the reliability of a consensus-based semiquantitative colour Doppler US scoring system for pathologic salivary gland vascularization in patients with primary Sjögren\"s syndrome (pSS). METHODS: Using the Delphi method, a colour Doppler semiquantitative scoring system for vascularization of bilateral parotid and submandibular glands was developed and tested in static images and on patients (9 pSS patients and 9 sonographers). Intra-reader and inter-reader reliability of grading the salivary glands were computed by weighted Cohen and Light\"s kappa analysis, respectively. RESULTS: The consensus-based semiquantitative score was: grade 0, no visible vascular signals; grade 1, focal, dispersed vascular signals; grade 2, diffuse vascular signals detected in 50% of the gland. In static images, the intra- and inter-reader reliability showed excellent kappa values (95% CI) of 0.90 (0.87, 0.93) and 0.80 (0.74, 0.84), respectively, for all four salivary glands together. In patients, the intra- and inter-reader reliability for all four salivary glands together was kappa = 0.84 (0.73, 0.92) and 0.70 (0.64, 0.76), respectively. CONCLUSION: The consensus-based colour Doppler US scoring for the evaluation of salivary gland vascularization in pSS showed a good inter-reader reliability and excellent intra-reader reliability in static images and in patients. The clinical application of the developed scoring system should be tested in clinical settings.
dc.identifier.citationHočevar A., Bruyn G. A. , Terslev L., De Agustin J. J. , MacCarter D., Chrysidis S., Collado P., Dejaco C., Fana V., Filippou G., et al., "Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjögren's syndrome: an OMERACT reliability exercise", Rheumatology (Oxford, England), cilt.61, sa.8, ss.3341-3350, 2022
dc.identifier.doi10.1093/rheumatology/keab876
dc.identifier.endpage3350
dc.identifier.issn1462-0332
dc.identifier.issue8
dc.identifier.startpage3341
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85135596590&origin=inward
dc.identifier.urihttps://hdl.handle.net/11424/283979
dc.identifier.volume61
dc.language.isoeng
dc.relation.ispartofRheumatology (Oxford, England)
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectTıp
dc.subjectTemel Eczacılık Bilimleri
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectİmmünoloji ve Romatoloji
dc.subjectEczacılık
dc.subjectYaşam Bilimleri
dc.subjectSağlık Bilimleri
dc.subjectTemel Bilimler
dc.subjectMedicine
dc.subjectBasic Pharmaceutics Sciences
dc.subjectInternal Medicine Sciences
dc.subjectInternal Diseases
dc.subjectImmunology and Rheumatology
dc.subjectPharmacology and Therapeutics
dc.subjectLife Sciences
dc.subjectHealth Sciences
dc.subjectNatural Sciences
dc.subjectKlinik Tıp (MED)
dc.subjectYaşam Bilimleri (LIFE)
dc.subjectKlinik Tıp
dc.subjectFarmakoloji ve Toksikoloji
dc.subjectROMATOLOJİ
dc.subjectFARMAKOLOJİ VE ECZACILIK
dc.subjectClinical Medicine (MED)
dc.subjectLife Sciences (LIFE)
dc.subjectCLINICAL MEDICINE
dc.subjectPHARMACOLOGY & TOXICOLOGY
dc.subjectRHEUMATOLOGY
dc.subjectPHARMACOLOGY & PHARMACY
dc.subjectRomatoloji
dc.subjectFarmakoloji (tıbbi)
dc.subjectRheumatology
dc.subjectPharmacology (medical)
dc.subjectprimary Sjogren's syndrome
dc.subjectsalivary gland vascularization
dc.subjectcolour Doppler ultrasound
dc.subjectscoring system
dc.subjectCOLOR DOPPLER SONOGRAPHY
dc.subjectCLASSIFICATION CRITERIA
dc.subjectSALIVARY-GLANDS
dc.subjectCONSENSUS
dc.subjectprimary Sjögren’s syndrome
dc.titleDevelopment of a new ultrasound scoring system to evaluate glandular inflammation in Sjögren's syndrome: an OMERACT reliability exercise
dc.typearticle
dspace.entity.typePublication
local.avesis.id0f95d90f-1920-4316-a9af-2a74a0052c6e
local.indexed.atWOS
local.indexed.atPUBMED
local.indexed.atSCOPUS
relation.isAuthorOfPublicationc963a17b-4775-4dd7-8db7-ea072cc49ef1
relation.isAuthorOfPublication.latestForDiscoveryc963a17b-4775-4dd7-8db7-ea072cc49ef1

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